TechNet-21 - Forum

This forum provides a place for members to ask questions, share experiences, coordinate activities, and discuss recent developments in immunization.
  1. Deleted User
  2. Service delivery
  3. Tuesday, 01 July 2014

The following guidance documents are now available:

PRACTICES TO IMPROVE COVERAGE OF THE HEPATITIS B BIRTH DOSE VACCINE
This document is now available in both English and French. The main purpose of this document is to evaluate published and grey literature on best practices for provision of hepatitis B vaccine to newborns. The document examines which practices improve coverage and describes facilitators and barriers to improving coverage of the birth dose.

DOCUMENTING THE IMPACT OF HEPATITIS B IMMUNIZATION: BEST PRACTICES FOR CONDUCTING A SEROSURVEY
This document is now available in both English and French. This document describes best practices for implementing hepatitis B serosurveys, including survey design, sampling, field methods, and data analysis.

Omesh K. Bharti Accepted Answer

We Should explore low cost ID routes in all vaccines including Hep B

Thereafter, this route ID, has been tried in special groups as well as in non-responders to IM vaccine. In patients with chronic kidney disease or on maintenance dialysis, whether hepatitis B vaccine-naïve or non-responders to prior IM vaccine series, ID administration has been found, in several randomized trials and systematic reviews, to be associated with higher seroconversion rates as well as antibody titers.[11-13] In another study, 69% of 42 non-responders with chronic liver disease seroconverted after a 3-dose ID regimen.[14] Similarly, children with celiac disease who had not responded to infant hepatitis B immunization and were randomly assigned to receive boosters by ID route seroconverted earlier and with higher anti-HBs levels than those assigned to IM boosters.[15] Also, in observational studies, a large proportion of non-responders who were otherwise healthy have been found to seroconvert following ID doses of the vaccine.

http://onlinelibrary.wiley.com/doi/10.1111/jgh.13234/full

  1. more than a month ago
  2. Service delivery
  3. # 1


There are no replies made for this post yet.
Be one of the first to reply to this post!