POST 01175E : VACCINE-DERIVED POLIO VIRUS

POST 01175E : VACCINE-DERIVED POLIO VIRUS 22 October 2007 _______________________________________ We wish to draw your attention to the Weekly Epidemiological Report of 28 September 2007 that featured a "Global update on vaccine-derived polioviruses, January 2006 - August 2007" Since 2000, increasing evidence has affirmed the need for a comprehensive strategy to reduce and manage the risk of polio cases and polio outbreaks caused by vaccine-derived polioviruses (VDPVs), particularly following the interruption of transmission of wild poliovirus (WPV) globally. Central to that strategy is a thorough understanding of VDPVs, especially their capacity (i) to cause polio outbreaks in areas with low rates of coverage with oral poliovirus vaccine (OPV) and (ii) to replicate for prolonged periods in some immunodeficient individuals with defects in antibody production. This report updates the summary on VDPVs previously published, with a description of VDPVs detected in 2006 and 2007. ______________________________________________________________________________ All members of the TechNet21 e-Forum are invited to send comments on any posting or to use the forum to raise a new discussion or request technical information in relation to immunization services. The comments made in this forum are the sole responsibility of the writers and do not in any way mean that they are endorsed by any of the organizations and agencies to which the authors may belong. ______________________________________________________________________________ Visit the TECHNET21 Website at http://www.technet21.org You will find instructions to subscribe, a direct access to archives, links to reference documents and other features. ______________________________________________________________________________ To UNSUBSCRIBE, send a message to : [[email protected]][email protected][/email] Leave the subject area BLANK In the message body, write unsubscribe TECHNET21E ______________________________________________________________________________ The World Health Organization and UNICEF support TechNet21. The TechNet21 e-Forum is a communication/information tool for generation of ideas on how to improve immunization services. It is moderated by Claude Letarte and is hosted in cooperation with the Centre de coopération internationale en santé et développement, Québec, Canada (www.ccisd.org ______________________________________________________________________________