Pezzoli Epi Infect 2011

Publication Abstract: We used the clustered lot quality assurance sampling (clustered-LQAS) technique to identify districts with low immunization coverage and guide mop-up actions during the last 4 days of a combined oral polio vaccine (OPV) and yellow fever (YF) vaccination campaign conducted in Cameroon in May 2009. We monitored 17 pre-selected districts at risk for low coverage. We designed LQAS plans to

reject districts with YF vaccination coverage <90% and with OPV

coverage <95%. In each lot the sample size was 50 (five clusters

of 10) with decision values of 3 for assessing OPV and 7 for YF

coverage. We ‘ rejected’ 10 districts for low YF coverage and 14

for low OPV coverage. Hence we recommended a 2-day extension of the

campaign. Clustered- LQAS proved to be useful in guiding the

campaign vaccination strategy before the completion of the

operations.