Vaccine management processes are designed to ensure product quality and comprises an integrated system of equipment, procedures, records, and activities. Effective vaccine management requires that personnel who handle and distribute vaccines have the education, training, and experience required to perform their jobs effectively. In short, they must have expertise. This course is meant to provide the background and context for the ultra-cold chain management for emergency Ebola vaccination and certain COVID-19 vaccines. The course aims to build a mental model in ULT vaccine management.