60 results
In 2020, WHO developed an MS Excel-based tool designed for defining the most suitable vaccination session frequency from vaccine wastage outputs. The tool provides simulations for changing service...
The site contains a range of tools and guidelines that include the following: Setting a standard for the vaccine supply chain, EVM background and training resources, EVM Standard Operating...
The website aims to serve as a central knowledge repository for projects with healthcare waste components in developing countries.
This document is a summary of how to store and handle the Pfizer-BioNTech COVID-19 Vaccine
This resource
is a culmination of DPCP research results to provide decision makers with evidence that can be generalized to other countries when considering vaccine presentation.
The purpose of this study is to test the utilization of VVMs by the health
personnel in the field and to monitor the change in vaccine wastage rates with the
introduction of VVMs and open vial...
This study was conducted to test under field conditions a
methodology for evaluating the capacity of VVMs to (i) reduce vaccine wastage and
(ii) monitor the status of the cold chain at the point of...
Vaccine temperature control failures represent a significant public and private healthcare cost. Vaccines damaged by excessive heat or freezing lose their effectiveness, putting public health at...
This executive summary details the key findings from the 5-dose MCV research in Zambia: improved coverage, reduced wastage, no cold chain constraints, and healthcare workers were more willing to open...
This case study describes the impact of changing to 5-dose measles containing vaccine in Zambia with improved coverage, lower wastage rate and no cold chain constraints.
In Cambodia, we assessed vaccine wastage-related vaccinator knowledge and practices.
To help immunization stakeholders make effective DPC decisions for their country context, the Dose Per Container Partnership (DPCP) has developed generalized information based on the partnership’s...
This resource is a culmination of DPCP research results to provide decision makers with evidence that can be generalized to other countries when considering vaccine presentation.
Country- and...
Vietnam: Effects of Changing Dose per Container on the Immunization System
Vaccination in Zambia - Healthworker Experiences Using 5-dose MR Vaccine
Senegal: Weighing the Costs and Benefits of Changing DPC
Modeling to Support Decision-Making for 5-dose Measles-Rubella Routine Vaccination in Zambia
Measles Vaccination in Zambia: Balancing Coverage & Wastage
Information Gaps in Decision-Making on Vaccine Presentation in 3 Francophone Countries
Immunization Tools to Help the Dose Per Container Decision
Ghana: Understanding Changes in Vaccine Presentation
This Facts Sheet informs of the availability of Measles vaccine and combined Measles-Rubella (MR) vaccine in both a 10-dose vial and a 5-dose vial presentations through (or via) UNICEF procurement.
Objectives: Cold chain control is one of the most important facts to ensure the effectiveness of vaccines links, which requires specific material and human resources for management. The principal...
BACKGROUND: Vaccines should be stored and handled according to manufacturer specifications. Inadequate cold chain management can affect potency; but, limited data exist on adverse events (AE)...
INTRODUCTION: The quality of vaccines is critical for good immunization outcomes. It is dependent on the effectiveness of technical and logistics management system put in place. This study aimed to...
BACKGROUND AND AIM OF THE STUDY: The principles of „cold chain” have been developed for the safe transport and storage of vaccines because of their sensitivity to temperature and are guidelines...
Inadvertent vaccine freezing often occurs in the cold chain and may cause damage to freeze‑sensitive vaccines. Liquid vaccines that contain aluminum salt adjuvants are particularly vulnerable....
Background: We assessed programmatic adaptations and infants\' uptake of inactivated poliovirus vaccine (IPV) after its introduction into the routine immunization schedule in Bangladesh. Methods:...
ackground
While our previous work has shown that replacing existing vaccines with thermostable vaccines can relieve bottlenecks in vaccine supply chains and thus increase vaccine availability, the...
Insoluble aluminum salts such as aluminum oxyhydroxide have been used for decades as adjuvants in human vaccines, and many vaccines contain aluminum salts as adjuvants. Aluminum salt-adjuvanted...
Lyophilization of vaccines is advantageous for the distribution and storage of thermally labile products, particularly in regions where cold chain management is difficult. To date, current...
The following is a DRAFT set of Preferred Product Characteristics (PPC) for a generic microarray patch (MAP) presentation) with a solid vaccine formulation of a live-attenuated measles-rubella (MR)...
OBJECTIVES:
Cold chain control is one of the most important facts to ensure the effectiveness of vaccines links, which requires specific material and human resources for management. The principal...
The Technet meeting was held from 26-27 October 2006 in Mexico city. Over 120 participants attended the conference. This report summarises the discussions.
Technet was relaunched at the 2001 conference as Technet21. The New Delhi 2001 meeting, organized back-to-back with SIGN, welcomed a total of 107 participants including 23 participants representing...
Developed jointly by UNICEF and WHO, this brief \"MDVP\" mini-course provides all partners and staff working to support immunization with a better understanding of the 2014 revision of the Multi-Dose...
Background: Two-dimensional (2D) barcoding has the potential to enhance documentation of vaccine encounters at the point of care. However, this is currently limited to environments equipped with...
Background
Many countries, such as Niger, are considering changing their vaccine vial size presentation and may want to evaluate the subsequent impact on their supply chains, the series of steps...
The purpose of this paper is to present results of tests conducted to determine the \"warm life\" of a well known vaccine carrier, witand without simple modifications. The information presented in...
Introduction:
People who handle and regulate temperature-sensitive pharmaceutical products require the knowledge and skills to ensure those products maintain quality, integrity, safety, and...
The dangers of accidental freezing of vaccines in the cold chain have prompted studies throughout the globe to better characterize the risk. To date, there has been no systematic review of these...
PPT summarising WHO informal consultation to develop further guidance on vaccines for the UNEP-convened Intergovernmental Negotiating Committee Meeting 4 (INC4)
This study captures the perspectives of stakeholders at multiple levels of the vaccine supply chain regarding their assessment of challenges with storing vaccines within recommended temperature...
WHO and UNICEF supported Ghana to conduct Effective Vaccine Management (EVM) assessments in September 2010 and October 2014 respectively with the view to strengthening vaccine and logistics...
Antigens contained in vaccines are inherently unstable biologically; such a characteristic is conferred by their three-dimensional structure. Preserving the ability of the vaccines to protect against...
Introduced to minimize open vial wastage, single-dose vaccine vials require more storage space and therefore may affect vaccine supply chains (i.e., the series of steps and processes involved in...
Le présent module indique comment se servir correctement de conteneurs passifs (glacières et porte-vaccins) pour le transport domestique et les opérations en périphérie.
The efficacy of vaccines can be compromised by faulty transport, storage, and handling. This study was conducted to assess the knowledge and practice of vaccine storage and handling among Primary...
This study is the first systematic documentation of the potency of monovalent oral polio vaccine type 3 (mOPV3) kept at ambient temperatures during a polio immunization campaign in Chad. During the...
This study was planned to evaluate structural damages in adsorbed vaccines affected by freezing using scanning electron microscopy and X-ray analysis of the elements. Randomly selected 42 vials of...
Research Question: What is the vaccine wastage in a primary care setting in urban India?
Methods: Record based descriptive study carried out in an Immunisation clinic in an urban resettlement...
Making any EPI vaccine thermostable relieved existing supply chain bottlenecks (especially at the lowest levels), increased vaccine availability of all EPI vaccines, and decreased cold storage and...
Open vial vaccine wastage in multi-dose vials is a major contributor to vaccine wastage. Although switching from 10-dose vials to 5-dose vials could reduce wastage, a higher total cost could be...
Many vaccines are manufactured in large, multi-dose vials that once opened, must be used within a matter of hours. As a result, clinicians (especially those in remote locations) face difficult...
This report presents the first year of a multi-year evaluation into medical supply reform in Papua New Guinea (PNG). This report presents the methods, findings and recommendations and is intended for...
This module of the WHO Vaccine Management Handbook (VMH) provides guidance on how to develop a transport strategy that minimizes the risk of exposure to freezing through the correct use of passive...
VaCRO is an Excel based tool that helps clinicians minimize open vial waste while maximizing immunization coverage by using the mathematical models to determine cut-off times for which it is optimal...
The purpose of this document is to provide up-to-date information to support countries in making informed decisions around the appropriate yellow fever vaccine (YFV) vial presentations for routine...