Showing 48 of 48 results

CDC - Centers for Disease Control and Prevention
Guidelines for the Preparation and Administration Summary of Janssen COVID-19 Vaccine (Johnson & Johnson)
Dose Per Container Partnership
This executive summary details the key findings from the 5-dose MCV research in Zambia: improved coverage, reduced wastage, no cold chain constraints, and healthcare workers were more willing to open...
BID Initiative
This webinar focuses on the practical aspects of managing the cold chain for a vaccination program in an environment that is less than ideal. The presenter highlights the successes, challenges,...
BID Initiative
This set of tools may be used for planning the introduction of a new intervention or activities prior to implementation of the intervention. These tools can help you to understand the landscape for...
BID Initiative
To increase coverage and equity of routine immunization services, the government of Tanzania is strengthening the data use culture through the implementation of a package of data quality and use...
BID Initiative
The BID Learning Network recently held a webinar called "Successful implementation of a Health information Software." In this webinar, the speakers shared Mali’s experience implementing health...
Dose Per Container Partnership
To help immunization stakeholders make effective DPC decisions for their country context, the Dose Per Container Partnership (DPCP) has developed generalized information based on the partnership’s...
Dose Per Container Partnership
This resource is a culmination of DPCP research results to provide decision makers with evidence that can be generalized to other countries when considering vaccine presentation. Country- and...
Inc., West Pharmaceutical Services
West Pharmaceutical Services, Inc. (NYSE: WST), a global leader in innovative solutions for injectable drug administration, today shared the results of a study highlighting the benefits of West\'s...
IPAC Delivery Technologies Working Group
As micro-array patches (MAPs, also known as microneedle patches) continue to be developed, their potential advantages of thermal stability and improved ease-of-use, and immunogenicity make them a...
Bekolo CE, van Loenhout JA, Rodriguez-Llanes JM, Rumunu J, Ramadan OP, Guha-Sapir D.
OBJECTIVE: To determine whether pre-emptive oral cholera vaccination reduces disease severity and mortality in people who develop cholera disease during an outbreak. METHODS: The study...
Darin Zehrung et al.
A variety of vaccine packaging and delivery technologies may benefit the immunization supply chain. These include alternative primary packaging, such as blow-fill-seal polymer containers, and novel...
Jarrahian et al.
Intradermal delivery of a fractional dose of inactivated poliovirus vaccine (IPV) offers potential benefits compared to intramuscular (IM) delivery, including possible cost reductions and easing of...
Yotam Levin, Efrat Kochba, Ivan Hung, Richard Kenney
Intradermal immunization has become a forefront of vaccine improvement, both scientifically and commercially. Newer technologies are being developed to address the need to reduce the dose required...
Izrail Tsals
Intradermal adapter device technology minimizes the complexity of the Mantoux technique, thereby providing predictable, reproducible intradermal (ID) injections and removing the concerns regarding...
Sonia Resik, Alina Tejeda, Ondrej Mach, Magile Fonseca, Manuel Diaz, Nilda Alemany, Gloria Garcia, Lai Heng Hung, Yenisleydis Martinez, Roland Sutter
The World Health Organization recommends that, as part of the new polio endgame, a dose of inactivated poliovirus vaccine (IPV) be introduced by the end of 2015 in all countries using only oral...
Jaya Arya, Mark R. Prausnitz
Millions of people die of infectious diseases each year, mostly in developing countries, which could largely be prevented by the use of vaccines. While immunization rates have risen since the...
Savitha Swaminathan, Sarah M. Bartsch, Mercy Mvundura, Mark R. Prausnitz, Kristina M. Zapf, Kathleen Marinan, James J. Norman, Erica Jacoby, Darin Zehrung, Courtney Jarrahian, Bruce Y. Lee, Bill Snyder, Angela R. Wateska
New vaccine technologies may improve the acceptability, delivery (potentially enabling self-administration), and product efficacy of influenza vaccines. One such technology is the microneedle patch...
Sachiko Hirobe, Hiroaki Azukizawa, Takaaki Hanafusa, Kazuhiko Matsuo, Ying-Shu Quan, Fumio Kamiyama, Ichiro Katayama, Naoki Okada, Shinsaku Nakagawa
Transcutaneous immunization (TCI) is an attractive vaccination method compared with conventional injectable vaccines because it is easier to administer without pain. We developed a dissolving...
Chris Edens, Naomi C. Dybdahl-Sissoko, William C. Weldon, M. Steven Oberste, Mark R. Prausnitz
The phased replacement of oral polio vaccine (OPV) with inactivated polio vaccine (IPV) is expected to significantly complicate mass vaccination campaigns, which are an important component of the...
Chris Edens, Marcus L. Collins, Jessica Ayers, Paul A. Rota, Mark R. Prausnitz
Measles vaccination programs would benefit from delivery methods that decrease cost, simplify logistics, and increase safety. Conventional subcutaneous injection is limited by the need for skilled...
Marcel B.M. Teunissen, Darin Zehrung
Vaccination is an acknowledged powerful intervention to reduce mortality and morbidity caused by infectious diseases, preventing 2.5 million deaths each year as estimated by the World Health...
Yuping Ambuel, Ginger Young, Joseph N. Brewoo, Joanna Paykel, Kim L. Weisgrau, Eva G. Rakasz, Aurelia A. Haller, Michael Royals, Claire Y.-H. Huang, Saverio Capuano, Dan T. Stinchcomb, Charalambos D. Partidos and Jorge E. Osorio
Dengue viruses (DENVs) cause approximately 390 million cases of DENV infections annually and over 3 billion people worldwide are at risk of infection. No dengue vaccine is currently available nor is...
Melissa M. Coughlin, Marcus Collins, Gene Saxon, Courtney Jarrahian, Darin Zehrung, Chris Cappello, Rajeev Dhere, Michael Royals, Mark Papania, Paul A. Rota
Disposable-syringe jet injectors (DSJIs) with single-use, auto disable, needle-free syringes offer the opportunity to avoid hazards associated with injection using a needle and syringe. Clinical...
Hennie D. Geldenhuys, Helen Mearns, Jennifer Foster, Eugene Saxon, Benjamin Kagina, Laura Saganic, Courtney Jarrahian, Michele D. Tameris, One B. Dintwe, Michele Van Rooyen, Kany-Kany A. Luabeya, Gregory Hussey, Thomas J. Scriba, Mark Hatherill, Darin Zehrung
Intradermal bacille Calmette-Guérin (BCG) vaccination by needle-free, disposable-syringe jet injectors (DSJI) is an alternative to the Mantoux method using needle and syringe (NS). We compared the...
Manjari Lal, Courtney Jarrahian, Changcheng Zhu, Nancy A. Hosken, Chris L. McClurkan, David M. Koelle, Eugene Saxon, Andrew Roehrig, Darin Zehrung, Dexiang Chen
Rotavirus infection, which can be prevented by vaccination, is responsible for a high burden of acute gastroenteritis disease in children, especially in low-income countries. An appropriate...
Manjari Lal, Courtney Jarrahian
Oral administration of vaccines is simpler and more acceptable than injection via needle and syringe, particularly for infants (Fig. 1) This route is promising for new vaccines in development against...
Abhijeet Ananda, K. Zamanb, Concepción F. Estívariza, Mohammad Yunusb, Howard E. Garya, William C. Weldona, Tajul I. Baric, M. Steven Oberstea, Steven G. Wassilaka, Stephen P. Lubyd, James D. Heffelfingera, Mark A. Pallanscha
Inactivated poliovirus vaccine (IPV) introduction and phased oral poliovirus vaccine (OPV) cessation are essential for eradication of polio. Healthy 6-week old infants in Bangladesh were...
Carlos Wong, Minghuan Jiang, Joyce H. S. You
The influenza vaccine coverage rate of children is low in Hong Kong. Microneedle patches (MNPs) is a technology under development for painless delivery of vaccines. This study aimed to examine the...
Richard W. Compans, Mark R. Prausnitz, Joshy Jacob, Ioanna Skountzou, Elena V. Vassilieva, E. Stein Esser, Andrey A. Romanyuk
Maternal and neonatal tetanus claim tens of thousands lives every year in developing countries, but could be prevented by hygienic practices and improved immunization of pregnant women. This study...
Erica Jacobya, Courtney Jarrahiana, Harry F. Hullb, Darin Zehrunga
Simple and efficacious delivery methods for influenza vaccines are needed to improve health outcomes and manage possible pandemics both in the United States and globally. One approach to meeting...
World Health Organization (WHO)
On 8 December 2015, the WHO Department for Immunization, Vaccines and Biologics convened patch developers, vaccine manufacturers, regulators, funders and other key stakeholders to discuss WHO...
PATH, Gavi, the Vaccine Alliance
This document aims to establish a common vaccine innovation vocabulary to help ensure clarity in communications about innovations applied to vaccine products to increase their programmatic...
The following is a DRAFT set of Preferred Product Characteristics (PPC) for a generic microarray patch (MAP) presentation) with a solid vaccine formulation of a live-attenuated measles-rubella (MR)...
Wouter F. Tonnis et al.
Pulmonary vaccine delivery has gained increasing attention during the last decade because this vaccination method combines potential advantages such as the fact that it omits the use of needles and...
Anne C. Moore, Laura J. Sahm, Sarah Marshall
OBJECTIVE: To examine published research which explores the perception and acceptability of microneedle technology for immunisation and to investigate the suitability of this technology for...
Deng Y & Winter G, Myschik J.
A very promising novel needle-free application method is epidermal powder immunisation, a method delivering particulate vaccines into the viable epidermis of human skin where a dense network of...
Sagar Makwana et al.
Parenteral administration of pharmaceutical products is one of the most popular methods used to produce quick onset of action and also 100% bioavailability. Main problem occurs with the parenteral...
Robert C. Seid Jr et al.
Transcutaneous immunization (TCI) has become an attractive alternate route of immunization due to increase understanding of the skin immune system and to recent technical innovations in skin patch...
Meyer J et al.
New vaccines to prevent tuberculosis are urgently needed. MVA85A is a novel viral vector TB vaccine candidate designed to boost BCG-induced immunity when delivered intradermally. To date,...
Darin Zehrung et al.
There is a wide range of methods and technologies aimed at improving human vaccine products and the way they are delivered. Some of these have the potential to increase vaccine effectiveness in...
JK Hickling et al.
Most vaccines are delivered by the intramuscular or subcutaneous routes using a needle and syringe; the intradermal route is only widely used for the administration of Bacille Calmette-Guérin and...
Zaffran M, Kristensen D
This article discusses the importance of designing vaccine products with attributes that will help to mitigate challenges that immunization programs are facing as they introduce new vaccines. The...
G. Garcia, L. Maillart, M. Mofrad, B. Norman, J. Rajgopal
VaCRO is an Excel based tool that helps clinicians minimize open vial waste while maximizing immunization coverage by using the mathematical models to determine cut-off times for which it is optimal...
Ken Gerlach, Patrick Koeppl, Regina Cox, Heather V. Evanson, Warren W. Williams, Michael Greene, Jenica Huddleston Reed, Leslie A. Fierro, Erin D. Kennedy, Ashley Daily
BACKGROUND AND OBJECTIVE Accurately recording vaccine lot number, expiration date, and product identifiers, in patient records is an important step in improving supply chain management and patient...