Showing 92 of 92 results

COSTVAC is an Excel-based toolkit that provides structured guidance on how to estimate the cost of routine immunization from a sample of health facilities and administrative levels of the health...
PATH.
In 2020, Ghana's switched from ROTARIX to ROTAVAC in its routine immunization program in order to save money and cold chain space. An economic analysis of this switch, conducted by PATH, the...
UNIVAC is a single universal vaccine impact and cost-effectiveness decision support model with a standardized, accessible Excel-based (now based in R), interface and a familiar set of input steps and...
PATH
Il s’agit d’un outil simple dans Excel qui permet d’évaluer et de comparer les coûts des programmes de vaccination antirotavirus pour chaque vaccin antirotavirus disponible sur le marché...
PATH
Remplacer un vaccin par un autre peut impacter significativement le budget national alloué à la vaccination. Pour le programme palestinien de vaccination contre le rotavirus, ce choix s’est...
PATH, Rostropovich-Vishnevskaya Foundation, Palestinian Ministry of Health
La vaccination antirotavirus en Palestine a considérablement fait diminuer la charge de morbidité que représente la diarrhée chez les enfants, et ses bénéfices ont été renforcés par un...
Gagandeep Kang, Jean-Pierre Amorij
Jean-Pierre Amorij (AH Consultancy), Norman Baylor (Biologics Consulting Group), Dilara Islam (AFRIMS), Gagandeep Kang (Christian Medical College), Beth Kirkpatrick (University of Vermont College of...
PATH.
Current live, oral rotavirus vaccines (LORVs) are reducing severe diarrhea in all settings, but they are not as effective in places with the highest burden. Alternative approaches in advanced...
PATH.
Current live, oral rotavirus vaccines (LORVs) are reducing severe diarrhea in all settings, but they are not as effective in places with the highest burden. Alternative approaches in advanced...
PATH.
Current live, oral rotavirus vaccines (LORVs) are reducing severe diarrhea in all settings, but they are not as effective in places with the highest burden. Alternative approaches in advanced...
Palestinian Ministry of Health, Rostropovich-Vishnevskaya Foundation, PATH
Rotavirus vaccination in Palestine has significantly reduced the burden of diarrhea among children, and the benefits were sustained through a vaccine product switch. In 2018, the Palestinian...
PATH
Middle-income countries not eligible for support from Gavi, the Vaccine Alliance, have been slow to introduce rotavirus vaccines, largely due to cost concerns. A PATH analysis shows that, in most...
Frédéric Debellut, Andrew Clark, Clint Pecenka, Jacqueline Tate, Ranju Baral, Colin Sanderson, Umesh Parashar, Deborah Atherly
Middle-income countries (MICs) that are not eligible for funding from Gavi, the Vaccine Alliance, have been slow to adopt rotavirus vaccines. Few studies have evaluated the cost-effectiveness and...
PATH
Switching from one vaccine product to another can have a significant impact on a country’s budget. For Palestine’s rotavirus vaccination program, a switch paid off. This brief describes an...
PATH
PATH’s Rotavirus Vaccine Cost Calculator is a simple, Excel-based tool for assessing and comparing costs of rotavirus vaccination programs annually and for a period of 10 years with each rotavirus...
World Health Organization (WHO)
This manual explains the most common procedures for rotavirus strain surveillance. Section 1 presents brief overviews of the methods and discusses implementation • issues. Sections 2-4 describe ...
World Health Organization (WHO)
This document provides background data regarding safety concerns of rotavirus vaccines and presents guidelines for routine post-marketing surveillance to assess the safety of rotavirus vaccines, with...
World Health Organization (WHO)
This information bulletin addresses the implications and required guidance associated with the upcoming scheduled shift in vaccine vial monitor (VVM) of the GlaxoSmithKline Biologicals SA (GSK)...
World Health Organization (WHO)
This generic protocol outlines a uniform approach to monitoring the impact of rotavirus vaccines that can be modified by countries to meet their specific needs. It provides background and...
World Health Organization (WHO)
This product fact sheet is intended for use by global and regional vaccine policy makers. The product fact sheet provides information on Rota procured by V3P reporting countries, including analyses...
Edited by Adam L. Cohen et al.
Vaccine has published a supplement entitled “Rotavirus Surveillance, Safety, and Economic Data before Vaccine Introduction: a Global Perspective from the World Health Organization Global Rotavirus...
Roger I.Glass et al.
Live oral rotavirus (RV) vaccines used worldwide are most effective in reducing diarrheal hospitalizations from RV in high income countries and least effective in low income countries where RV...
Batmunkh Nyambat, Kimberley Fox, Carl Kirkwood, Varja Grabovac, Wajid Abdul, Sodbayar Demberelsuren, Altansukh Enkhtuvshin, Amar Gongor, Narmandakh Javzandorj, Solongo Orosoo, Oyunchimeg Guntev, Sarangua Ganbold, Youngmee Jee, Altanchimeg Samdan
Background: Diarrheal disease is one of the leading causes of illness and death in young children in the world, especially the developing countries. Diarrheal disease results in about half a million...
Burke RM et al.
BACKGROUND: Rotavirus vaccines are less effective in developing countries versus developed countries. One hypothesis for this difference in performance is that higher levels of maternal antibodies in...
Bonkoungou IJO et al.
BACKGROUND: Burkina Faso was one of the first African nations to introduce pentavalent rotavirus vaccine (RV5, RotaTeq) into its national immunization program in October 2013. We describe the impact...
Robin P.Lazarus et al.
Background: Strategies are needed to improve oral rotavirus vaccine (RV), which provides sub-optimal protection in developing countries. Probiotics and zinc supplementation could improve RV...
Phillip Alexander Kittel
Background: Rotavirus is a highly contagious virus causing gastroenteritis, mostly in children under the age of 5. Since 2006, two vaccines are available in Germany. In 2013, these were included into...
Jason M. Mwenda et al.
Rotavirus is a leading cause of severe pediatric diarrhea globally, estimated to have caused 120,000 deaths among children aged <5 years in sub-Saharan Africa in 2013 (1). In 2009, the World Health...
Prasad S. Kulkarni et al.
Rotavirus is the most common cause of moderate-to-severe infant diarrhoea in developing countries, resulting in enormous morbidity, mortality, and economic burden. A bovine-human reassortant...
Doctors Without Borders / MSF-USA
Diarrhea is still one of the main killers in developing countries. Rotavirus is the main agent that causes severe gastroenteritis. It can very quickly lead to fatal dehydration, especially among very...
Sheila Isanaka et al.
Background: Each year, rotavirus gastroenteritis is responsible for about 37% of deaths from diarrhea among children younger than 5 years of age worldwide, with a disproportionate effect in...
Inácio Mandomando et al.
The 9th African rotavirus symposium was held in Maputo, Mozambique from the 8th to 10th of December 2015, including a total of 101 delegates from 17 countries, 15 of which were African countries....
International Vaccine Access Center (IVAC)
IVAC is releasing a set of tools capturing and synthesizing the latest and best available data around rotavirus diseases and vaccines with technical decision-makers in mind. We have developed a...
International Vaccine Access Center (IVAC)
The global analysis, entitled Gap Analysis of Rotavirus Vaccine Impact Evaluations in Settings of Routine Use, is the output of an IVAC-maintained database of completed and ongoing vaccine impact...
Wu W et al.
Rotavirus is a major cause of severe gastroenteritis among very young children. In developing countries, rotavirus is the major cause of mortality in children under five years old, causing up to 20%...
Manjari Lal, Courtney Jarrahian, Changcheng Zhu, Nancy A. Hosken, Chris L. McClurkan, David M. Koelle, Eugene Saxon, Andrew Roehrig, Darin Zehrung, Dexiang Chen
Rotavirus infection, which can be prevented by vaccination, is responsible for a high burden of acute gastroenteritis disease in children, especially in low-income countries. An appropriate...
Sara L. Thomas et al.
Introduction of infant oral rotavirus vaccination in the UK in July 2013 has resulted in decreased hospitalisations and Emergency Department (ED) visits for acute gastroenteritis (AGE), for both...
Lauren M. Schwartz et al.
Background The test-negative design (TND), an epidemiologic method currently used to measure rotavirus vaccine (RV) effectiveness, compares the vaccination status of rotavirus-positive cases and...
Indrani Mukhopadhya et al.
Background Rotaviruses (RV) are the leading cause of gastroenteritis in children less than five years of age worldwide. Rotarix®, a live attenuated monovalent vaccine containing a RV strain of...
Monica Lopez-Lacort et al.
Abstract Immunochromatography (ICG) is highly used in clinical settings for rotavirus (RV) diagnosis. The specificity of the tests differs by brand type and is not 100%, therefore its use when the...
Khitam Muhsen et al.
Background Uncertainty exists about the sustainability of the reduction in rotavirus gastroenteritis (RVGE) following the introduction of rotavirus vaccines into national immunization programs,...
International Vaccine Access Center (IVAC)
The 2016 Pneumonia and Diarrhea Progress Report: Reaching Goals Through Action and Innovation is the seventh annual Progress Report, but the first in the era of the Sustainable Development Goals...
Jacqueline E. Tate et al.
Background. Rotavirus vaccine efficacy is lower in low-income countries than in high-income countries. Rwanda was one of the first low-income countries in sub-Saharan Africa to introduce rotavirus...
Nigel A. Cunliffe, Naor Bar-Zeev, Aisleen Bennett
Widespread introduction of rotavirus vaccines has led to major reductions in the burden of rotavirus gastroenteritis worldwide. Vaccine effectiveness is diminished, however, in low income countries,...
Roma Chilengi et al.
Introduction: Under five mortality in Zambia is unacceptably high and diarrhoea is the third leading contributor. The Programme for Awareness and Elimination of Diarrhoea (PAED) sought to support the...
George Armah et al.
Background. The recommended schedule for receipt of 2-dose human rotavirus vaccine (HRV) coincides with receipt of the first and second doses of diphtheria, pertussis, and tetanus vaccine (ie, 6...
Ramani, Sasirekha et al.
Vaccine schedules including bivalent oral (bOPV) and inactivated (IPV) poliovirus vaccines will replace trivalent OPV (tOPV) in 2016. We evaluated rotavirus IgA seroresponses when the second dose of...
Maharaj K Bhan et al.
In The Lancet, findings from Nita Bhandari and colleagues\' phase 3 clinical trial1 show the safety and efficacy of the 116E rotavirus vaccine against severe rotavirus gastroenteritis in Indian...
Mary M. Agócs et al.
Since 2008, the World Health Organization (WHO) has coordinated the Global Rotavirus Surveillance Network, a network of sentinel surveillance hospitals and laboratories that report to ministries of...
Ryman TK et al.
Abstract BACKGROUND: Hygiene interventions reduce child mortality from diarrhea. Vaccination visits provide a platform for delivery of other health services but may overburden nurses. We compared 2...
Williams BA et al.
Understanding post-launch demand for new vaccines can help countries maximize the benefits of immunization programmes. In particular, low- and middle-income countries (LMICs) should ensure adequate...
Rota Council
An overview of the disease occurrence and what is needed to stop illnesses and deaths.
Maria Y.T. Ichihara et al.
Rotavirus is one of the leading cause of hospitalization and outpatients visits among children under five years. This study evaluated the overall and genotype-specific vaccine effectiveness of oral...
Centers for Disease Control and Prevention (CDC)
Rotavirus disease is the leading cause of childhood morbidity and mortality related to diarrhea in Latin America and the Caribbean (LAC), where an estimated 8,000 deaths related to rotavirus diarrhea...
Fidèle Ngabo et al.
The number of admissions to hospital for diarrhoea and rotavirus in Rwanda fell substantially after rotavirus vaccine implementation, including among older children age-ineligible for vaccination,...
Jeannette L. Comeau et al.
In November 2011, the province of Quebec, Canada implemented a publicly funded rotavirus (RV) vaccination program using the monovalent RV vaccine (RV1). To assess its impact, trends in passive RV...
Collette Abbott, Benjamin Tiede, George Armah, Adel Mahmoud
Globally, rotavirus gastroenteritis is the most common identifiable cause of severe diarrhea in children under 5. Recently introduced rotavirus vaccines from Merck & Co. and GlaxoSmithKline have the...
Joseph S. Zickafoose et al.
The study sought to determine whether hospital discharges for intussusception in children younger than 1 year have changed since the reintroduction of rotavirus vaccine in the United States.
Tu HA et al.
Rotavirus is the most common cause of severe diarrhoea worldwide. Vietnam is situated in the region of high rotavirus infection incidence and eligible for financial support to introduce rotavirus...
Greice Madeleine Ikeda do Carmo et al.
After the introduction of rotavirus vaccination for infants, significant declines for three full years were observed in under-5-y diarrhea-related mortality and hospital admissions for diarrhea in...
Donna M. MacDougall et al.
In Canada, rotavirus vaccine is recommended for all infants, but not all provinces/territories have publicly funded programs. The researchers compared public and healthcare provider (HCP) knowledge,...
Corinna Köster et al.
Rotaviruses are the leading reason for dehydration and severe diarrheal disease and in infants and young children worldwide. An increasing number of related publications cause a crucial challenge to...
Greice Madeleine Ikeda do Carmo et al.
In 2006, Brazil began routine immunization of infants <15 wk of age with a single-strain rotavirus vaccine. The researchers evaluated whether the rotavirus vaccination program was associated with...
Kerdpanich A et al.
The lyophilized formulation of the human rotavirus vaccine, RIX4414 (Rotarix™), is recommended to be stored at 2°C-8°C for optimal immunogenicity. In some settings with inadequate infrastructure...
Lou JT et al.
The study revealed that rotavirus is the leading cause of severe diarrhea of children in Hangzhou, especially for children <2 years, which highlight the need of widespread rotavirus immunization for...
N Parez et al.
Rotavirus gastroenteritis is a vaccine-preventable disease that confers a high medical and economic burden in more developed countries and can be fatal in less developed countries. Two vaccines with...
Alia Makki, Amani Mustafa, Manish Patel, Umesh Parashar, Tarak Trivedi, Nadia Teleb, Salah Haithami, Omer Siddig
The high burden of rotavirus disease in Sudan indicates that the recently implemented vaccination program should substantially improve child health in Sudan. This nationwide rotavirus surveillance...
Eyal Leshem et al.
Concerns exist about whether monovalent (RV1) and pentavalent (RV5) rotavirus vaccines provide adequate protection against diverse strains and whether vaccine introduction will lead to selective...
Dóró R et al.
Comprehensive reviews of pre licensure rotavirus strain prevalence data indicated the global importance of six rotavirus genotypes, G1P[8], G2P[4], G3P[8], G4P[8], G9P[8] and G12P[8]. Since 2006, two...
Jorien Veldwijk et al.
Highlights •Parental preferences and expected coverage may guide the introduction of rotavirus vaccines. •Vaccination decisions of parents were mostly driven by vaccine related out-of-pocket...
David RL & Kirk MD
To determine the effect of rotavirus vaccination on rotavirus hospitalisations in children under 5 years of age at The Canberra Hospital, Australian Capital Territory. Methods: Rotavirus...
George E. Armah et al.
Oral rhesus/rhesus-human reassortant rotavirus tetravalent (RRV-TV) vaccine was licensed in 1998 but withdrawn in 1999 due to a rare association with intussusception, which occurred...
Alyssa Morin, Arnaud Gagneur, Nathalie Carrier, Anne Farrands, Thomas Lemaître
In July 2010, the National Advisory Committee on Immunization (NACI) recommended the systematic administration of rotavirus vaccines for all infants in Canada. According to the Erickson and De Wals...
Masukawa Mde L et al.
The aim of this study is to investigate the impact of rotavirus vaccine on hospitalization rates for acute diarrhea in children younger than 5 years old after the introduction of the vaccine in 2006....
Escolano S et al.
The increased risk of intussusception after vaccination with the rhesus-human reassortant rotavirus vaccine Rotashield led to its withdrawal in 2005. The researchers assess the risk of...
Noga Givon-Lavi et al.
The study seeks to determine the effect of rotavirus-vaccines on the incidence of hospital visits due to rotavirus gastroenteritis (RVGE) and all-cause diarrhea in Jewish and Bedouin children <5 year...
Manish Patel et al.
The researchers observed a significant correlation between IgA titers and rotavirus vaccine efficacy and hypothesize that a critical level of IgA antibody titer is associated with a sufficient level...
Gagandeep Kang et al.
India accounts for 22% of the 453,000 global rotavirus deaths among children <5 years annually. The Indian Rotavirus Strain Surveillance Network provides clinicians and public health partners with...
Rishi Desai et al.
With the recent postlicensure identification of an increased risk of intussusception with rotavirus vaccine, the 14 Latin American countries currently using rotavirus vaccine must now weigh the...
The 11th International Rotavirus Symposium brought together over 650 people from 56 countries in New Delhi, India, from 3-5 September, 2014 to examine new surveillance data and studies demonstrating...
Stéphane Verguet et al.
The researchers incorporate financial risk protection and distributional consequences into the systematic economic evaluation of vaccine policy, illustrated here with the case study of public finance...
Penina Haber et al.
In 2006 and 2008, two new rotavirus vaccines (RotaTeq [RV5] and Rotarix [RV1]) were introduced in the United States. US data on intussusception have been mostly related to RV5, with limited data on...
Suzanne L. Pollard, Tanya Malpica-Llanos, et al.
Diarrhea is one of the leading causes of death in children under 5, and an estimated 39% of these deaths are attributable to rotavirus. Currently two live, oral rotavirus vaccines have been...
Guh- Alice Y & Hadler- James L
Immunization information systems (IIS) contain individual vaccination records and have potential use for evaluating post-licensure vaccine effectiveness (VE). A matched case-control study was...
Sahni- Leila C, Boom- Julie A, Patel- Manish M, Baker- Carol J, Rench- Marcia A, Parashar- Umesh D & Tate- Jacqueline E
Immunization information systems (IISs) are accessible sources of immunization data. We validated immunization information from a local IIS against provider records and assessed the system's utility...
Cortese- Margaret M, Leblanc- Julie, White- Karen E, Jerris- Robert C, Stinchfield- Patricia, Preston- Kenan L, Meek- James, Odofin- Lynda, Khizer- Saadia, Miller- Claudia A, Buttery- Vicki, Mijatovic-Rustempasic- Slavica, Lewis- Jamie, Parashar- Umesh D & Immergluck- Lilly Cheng
OBJECTIVE: Electronic immunization information systems (IISs) are now established in almost all US states. We used the IIS in Minnesota- Georgia- and Connecticut for immunization data and as the...
Fernando De la Hoz, Luz A. Chocontá Piraquive, Natalia Cediel, Alexandra Porras, Alejandro Rico, Nelson Alvis-Guzmán, Karol Cotes
OBJECTIVE: Estimate the effectiveness of the monovalent rotavirus vaccine in preventing the need to hospitalize children under 2 years old for acute diarrheal disease in five Colombian cities....