Showing 99 of 102 results

Chair David Spiro (NIAID/NIH)
R. Donis (US CDC), R. Rappuoli (Novartis), G. Nabel (Sanofi), N. Baylor (Biologics Consulting), P. Palese (Mt. Sinai), H. Golding (US FDA)
The purpose of this document is to outline the key theoretical concepts and best practice in methodologies, and to provide guidance on the economic evaluation of influenza vaccination in LMICs. The...
The WHO Flutool plus - Seasonal Influenza Immunization Costing Tool (SIICT) is an update of the previous Flutool and helps to project total costs of influenza vaccine introduction for different risk...
Kanta Subbarao, WHO Collaborating Centre for Reference and Research on Influenza
Options for pandemic influenza vaccines and challenges of universal influenza vaccine development
World Health Organization (WHO)
To support national immunization programme managers to optimize the introduction and implementation of influenza immunization programmes in countries, WHO has developed the Influenza Post...
World Health Organization (WHO)
National governments require economic data on the burden of influenza disease, the cost effectiveness of the vaccine, and the projected implementation costs of a maternal influenza immunization...
World Health Organization (WHO)
WHO has developed an introduction manual for national immunization programme managers and policy-makers to support the introduction of influenza immunization of pregnant women. This document aims...
World Health Organization (WHO)
WHO has developed an introduction manual for national immunization programme managers and policy-makers to support the introduction of health worker influenza immunization.
Tania F.Bahamondez-Canas & ZhengrongCui
Vaccination represents a cost-effective weapon for disease prevention and has proven to dramatically reduce the incidences of several diseases that once were responsible for significant mortality and...
Anika Singanayagam, Maria Zambon, Ajit Lalvani, Wendy Barclay
Conflicting reports have emerged about the effectiveness of the live attenuated influenza vaccine. The live attenuated influenza vaccine appears to protect particularly poorly against currently...
Bert Baumgaertner, Juliet E. Carlisle, Florian Justwan
In light of the increasing refusal of some parents to vaccinate children, public health strategies have focused on increasing knowledge and awareness based on a “knowledge-deficit” approach....
Pieter T. de Boer et al.
Background: To inform national healthcare authorities whether quadrivalent influenza vaccines (QIVs) provide better value for money than trivalent influenza vaccines (TIVs), we assessed the...
Phillips A et al.
AIM: To identify and describe potentially vaccine-preventable child deaths in New South Wales (NSW). METHODS: Child deaths in NSW from 2005 to 2014 potentially preventable by vaccination were...
PetraZimmermann & NigelCurtis
The immunomodulatory effects of probiotics may influence the response to vaccines. We systematically reviewed prospective randomised placebo-controlled studies in humans that have investigated the...
American Academy of Pediatrics (AAP)
All health care professionals who provide primary care to children and adolescents should always include routinely recommended vaccines as a part of the care that they deliver in the medical home....
Yoshio Hirota et al.
In Japan, the Vaccine Epidemiology Research Group created by the Ministry of Health, Labour and Welfare has played an important role in demonstrating the solid scientific basis for vaccine efficacy...
Katja HöschlerEmail the author Katja Höschler & Maria C Zambon
Despite strong recommendations, influenza vaccine uptake data for the UK for 2015–16 show that actual uptake in the population targeted lags behind the goal of the national vaccine programme,1...
Rouphael, N. et al.
Microneedle patches provide an alternative to conventional needle-and-syringe immunisation, and potentially offer improved immunogenicity, simplicity, cost-effectiveness, acceptability, and safety....
Holubar M et al.
BACKGROUND: Inclusion of vaccine herd-protection effects in cost-effectiveness analyses (CEAs) can impact the CEAs-conclusions. However, empirical epidemiologic data on the size of herd-protection...
Savitha Swaminathan, Sarah M. Bartsch, Mercy Mvundura, Mark R. Prausnitz, Kristina M. Zapf, Kathleen Marinan, James J. Norman, Erica Jacoby, Darin Zehrung, Courtney Jarrahian, Bruce Y. Lee, Bill Snyder, Angela R. Wateska
New vaccine technologies may improve the acceptability, delivery (potentially enabling self-administration), and product efficacy of influenza vaccines. One such technology is the microneedle patch...
Sachiko Hirobe, Hiroaki Azukizawa, Takaaki Hanafusa, Kazuhiko Matsuo, Ying-Shu Quan, Fumio Kamiyama, Ichiro Katayama, Naoki Okada, Shinsaku Nakagawa
Transcutaneous immunization (TCI) is an attractive vaccination method compared with conventional injectable vaccines because it is easier to administer without pain. We developed a dissolving...
Carlos Wong, Minghuan Jiang, Joyce H. S. You
The influenza vaccine coverage rate of children is low in Hong Kong. Microneedle patches (MNPs) is a technology under development for painless delivery of vaccines. This study aimed to examine the...
Erica Jacobya, Courtney Jarrahiana, Harry F. Hullb, Darin Zehrunga
Simple and efficacious delivery methods for influenza vaccines are needed to improve health outcomes and manage possible pandemics both in the United States and globally. One approach to meeting...
Donatella Panatto, Roberto Gasparini, Joan Puig-Barberà, Daniela Amicizia , Lucia Arata, Alexander Domnich
In the elderly, traditional influenza inactivated vaccines are often only modestly immunogenic, owing to immunosenescence. Given that adjuvantation is a means of enhancing the immune response, the...
Isaac G. Sakala et al.
The serious consequences of influenza infection during pregnancy have been recognized for almost a century. In this article, we reviewed the evidence on the immunogenicity, safety and impact of...
Julie A. Bettinger, Natasha Crowcroft, Shelley L. Deeks, Dean Fergusson, Kim Marty, Cameron Bell, Jacqueline Westeinde, Katherine M. Atkinson, Kumanan Wilson
The Canadian National Vaccine Safety network (CANVAS) gathers and analyzes safety data on individuals receiving the influenza vaccine during the early stages of annual influenza vaccination campaigns...
Cutrona, Sarah L, Sreedhara, Meera, Goff, Sarah L, Fisher, Lloyd D, Preusse, Peggy, Jackson, Madeline, Sundaresan, Devi, Garber, Lawrence D, Mazor, Kathleen M
BACKGROUND Clinical decision support (CDS), including computerized reminders for providers and patients, can improve health outcomes. CDS promoting influenza vaccination, delivered directly to...
Bay, Sarah L., Crawford, Daniel J.
Introduction Influenza presents additional burdens for children with chronic respiratory conditions. Influenza vaccinations may reduce complications, yet approximately half of children remain...
Justin R. Ortiz et al.
Introduction The WHO recommends annual influenza vaccination to prevent influenza illness in high-risk groups. Little is known about national influenza immunization policies globally. Material...
Marcel Verweij et al.
There has been increased interest in the potential of maternal immunisation to protect maternal, fetal, and infant health. Maternal tetanus vaccination is part of routine antenatal care and...
Milagritos D Tapia et al.
Background Despite the heightened risk of serious influenza during infancy, vaccination is not recommended in infants younger than 6 months. We aimed to assess the safety, immunogenicity, and...
Yoko Ibuka & Shun-ichiro Bessho
While studies have shown that reductions in out-of-pocket payments for vaccination generally encourages vaccination uptake, research on the impact on health outcomes has rarely been examined. Thus,...
Cutrona, Sarah L, Sreedhara, Meera, Goff, Sarah L, Fisher, Lloyd D, Preusse, Peggy, Jackson, Madeline, Sundaresan, Devi, Garber, Lawrence D, Mazor, Kathleen M
BACKGROUND: Clinical decision support (CDS), including computerized reminders for providers and patients, can improve health outcomes. CDS promoting influenza vaccination, delivered directly to...
Jane Tuckerman et al.
Several immunisations including influenza and pertussis are specifically recommended for healthcare workers (HCW) and childcare workers (CCW). This study aimed to assess community attitudes to HCW...
Sarah Marshall et al.
Microneedles (MNs) are designed to specifically target the outermost, skin barrier layer, the stratum corneum, creating transient pathways for minimally invasive transcutaneous delivery. It is...
Ramírez-Ramírez, Lilia L, Gel, Yulia R, Thompson, Mary, de Villa, Eileen, McPherson, Matt
In this paper we discuss the SIMID tool for simulation of the spread of infectious disease, enabling spatio-temporal visualization of the dynamics of influenza outbreaks. SIMID is based on modern...
YouXin Wang et al.
It is critical to distinguish events that are temporarily associated with, but not caused by, vaccination from those caused by vaccination during mass immunization. The researchers performed a...
Herrett, Emily, Williamson, Elizabeth, van Staa, Tjeerd, Ranopa, Michael, Free, Caroline, Chadborn, Tim, Goldacre, Ben, Smeeth, Liam
OBJECTIVES: (1) To develop methods for conducting cluster randomised trials of text messaging interventions utilising routine electronic health records at low cost; (2) to assess the effectiveness of...
Maartje Kristensen et al.
Implementation of additional targeted vaccinations to prevent infectious diseases in the older adults is under discussion in different countries. When considering the added value of such preventive...
Swamy GK & Garcia-Putnam R
Pregnant women are at risk for the same infectious diseases as nonpregnant individuals and often have increased morbidity and mortality associated with infection. Thus, immunizing women during...
Purssell E
Vaccination is an effective public health measure to prevent and control a number of infectious diseases. However, since vaccines are biological products and are sensitive to both heat and cold, they...
Marcel Salathé & Shashank Khandelwal
There is great interest in the dynamics of health behaviors in social networks and how they affect collective public health outcomes, but measuring population health behaviors over time and space...
Pedro L. Moro et al.
Vaccines are among the safest medical products in use today. Hundreds of millions of vaccinations are administered in the United States each year. Serious adverse reactions are uncommon. However,...
Laura Matrajt
Avian influenza A (H7N9), emerged in China in April 2013, sparking fears of a new, highly pathogenic, influenza pandemic. In addition, avian influenza A (H5N1) continues to circulate and remains a...
Tinglong Dai et al.
Although influenza vaccine shortage is often attributed to low supply, it has been observed that even with abundant supply, a major shortage can still occur due to late delivery. In this paper,...
Jon Smith et al.
For human vaccines to be available on a global scale, complex production methods, meticulous quality control, and reliable distribution channels are needed to ensure that the products are potent and...
Diamond MR & O\'Brien-Malone A
Multidose vials (MDVs) for injectable therapeutic agents, including vaccines, pose a risk of infection to injected patients as a result of contamination of the vials. The Australian Government...
Kristine Macartney, Nicholas Wood, Nigel Crawford, Christopher Blyth, Tom Snelling, Darren Westphal, Annette Regan, Alan Leeb, Patrick Cashman, Alexis Pillsbury
Increased febrile reactions in Australian children from one influenza vaccine brand in 2010 diminished confidence in influenza immunisation, highlighting the need for improved vaccine safety...
Sean P. Sullivan et al.
influenza prophylaxis would benefit from a vaccination method enabling simplified logistics and improved immunogenicity without the dangers posed by hypodermic needles. Here, we introduce dissolving...
Jean-Pierre Amorij et al.
Vaccination is the cornerstone of influenza control in epidemic and pandemic situations. Influenza vaccines are typically given by intramuscular injection. However, needle-free vaccinations could...
Yotam Levin et al.
Highlights •Low dose ID influenza vaccine immunogenicity can be equivalent to full dose IM. •A novel microneedle device induced higher responses compared to the Mantoux...
World Health Organization (WHO)
The World Health Organization (WHO) convenes technical consultations1 in February and September each year to recommend viruses for inclusion in influenza vaccines2 for the influenza season in...
Michael T Osterholm et al.
Influenza vaccines can provide moderate protection against virologically confirmed influenza, but such protection is greatly reduced or absent in some seasons. Evidence for protection in adults aged...
P.V. Effler, P.C. Richmond, D.B. Mak, L. Tracey, C.C. Blyth, A.K. Regan
OBJECTIVES: In 2013, the Follow-up and Active Surveillance of Trivalent Influenza Vaccine in Mums (FASTMum) program began using short message service (SMS) to collect adverse event information in...
W R Bowie, Julie A. Bettinger, Anne E. McCarthy, B L Coleman, Gaston De Serres, I Rouleau, James D. Kellner, L Valiquette, M C Gariépy, Otto G. Vanderkooi, S A McNeil
In 2011 and 2012, a nationwide Canadian vaccine safety surveillance network rapidly collected safety data from healthcare workers (HCW) during the first weeks of the annual influenza vaccination...
Andrew Dixon, Colleen Gately, Peter Lewis, Alice Laurence
OBJECTIVE: To estimate influenza and pneumococcal immunisation rates by self-report and validate this with immunisation providers. METHOD: A random population telephone survey. This was followed by...
Wood N and Siegrist CA
Recognition of the high burden of disease in early life and advances in the understanding of neonatal immunology have resulted in renewed interest in maternal and neonatal vaccination. This article...
Pernille Jorgensen et al.
In a severe pandemic, rapid production and deployment of vaccines will potentially be critical in mitigating the impact on populations and essential services. We compared access to vaccines and...
K. T. D. Eames
The impact of reactive school closure on an epidemic is uncertain, since it is not clear how an unplanned closure will affect social mixing patterns. The effect of school holidays on social mixing...
Global initiatives such as the Millennium Development Goals have led to major improvements in the health of women and children, and significant reductions in childhood mortality. Worldwide, maternal...
A. J. Elliot, E. O. Kara, P. Loveridge, Z. Bawa, R. A. Morbey, M. Moth, S. Large, G. E. Smith
Syndromic surveillance is an innovative surveillance tool used to support national surveillance programmes. Recent advances in the use of internet-based health data have demonstrated the potential...
Poehling- Katherine A, Vannoy- Lauren & Peters- Timothy R
BACKGROUND: The North Carolina Immunization Registry (NCIR) has been available since 2004. We sought to measure its utilization among practices that provide primary care for children who are enrolled...
Michelle Butler, Elissa Elvidge, Jody Stephenson, Craig Dalton, Sarah Moberley, Patrick Cashman, David N. Durrheim
Vaxtracker is a web based survey for active post marketing surveillance of Adverse Events Following Immunisation. It is designed to efficiently monitor vaccine safety of new vaccines by early signal...
Jones Cooper- Sorelle N & Walton-Moss- Benita
INTRODUCTION: Asthma is a major public health concern in the U.S. pediatric population. Children with asthma tend to fare worse when they acquire respiratory illnesses such as influenza- requiring...
Regan- Annette K, Blyth- Christopher C, Mak- Donna B, Richmond- Peter C & Effler- Paul V
BACKGROUND: Trivalent influenza vaccine (TIV) has been recommended for pregnant women in Australia for more than a decade and funded since 2009- yet vaccination coverage remains low. Misperceptions...
Herrett- Emily, van Staa- Tjeerd, Free- Caroline & Smeeth- Liam
INTRODUCTION: The UK government recommends that at least 75% of people aged under 64 with certain conditions receive an annual influenza vaccination. Primary care practices often fall short of this...
Harris- Katherine M, Schonlau- Matthias & Lurie- Nicole
We studied the feasibility of using an internet-based panel survey to obtain timely and accurate population-based data on influenza vaccination. We surveyed a nationally representative sample of US...
Stockwell- Melissa S, Hofstetter- Annika M, DuRivage- Nathalie, Barrett- Angela, Fernandez- Nadira, Vargas- Celibell Y & Camargo- Stewin
OBJECTIVE: To determine whether provision of vaccine-health-literacy-promoting information in text message vaccine reminders improves receipt and timeliness of the second dose of influenza vaccine...
Dombkowski- Kevin J, Cowan- Anne E, Potter- Rachel C, Dong- Shiming, Kolasa- Maureen & Clark- Sarah J
OBJECTIVES: We evaluated the use of a statewide immunization information system (IIS) to target influenza vaccine reminders to high-risk children during a pandemic. METHODS: We used Michigan's IIS to...
Bexelius- Christin, Merk- Hanna, Sandin- Sven, Ekman- Alexandra, Nyrén- Olof, K\{u}hlmann-Berenzon Sharon, Linde Annika & Litton Jan-Eric"
This study compared the use of Short Message Service (SMS) on mobile phones and the use of telephone interviews in collecting self-reported data about influenza vaccination. Through random selection...
Dombkowski- Kevin J, Harrington- Laura B, Dong- Shiming & Clark- Sarah J
BACKGROUND: Children with chronic conditions have an increased risk of complications from influenza and have low influenza vaccination rates. PURPOSE: To assess the feasibility and effectiveness of...
Stockwell- Melissa S, Catallozzi- Marina, Camargo- Stewin, Ramakrishnan- Rajasekhar, Holleran- Stephen, Findley- Sally E, Kukafka- Rita, Hofstetter- Annika M, Fernandez- Nadira & Vawdrey- David K
OBJECTIVE: To determine the impact of a vaccination reminder in an electronic health record supplemented with data from an immunization information system (IIS). METHODS: A noninterruptive influenza...
Dombkowski- Kevin J, Leung- Sonia W & Clark- Sarah J
OBJECTIVES: Despite longstanding national guidelines- many children with asthma do not receive annual influenza vaccinations. Information from Medicaid-administrative claims data was integrated into...
Van Rossem- In\`{e}s, Vandevoorde- Jan, Buyl- Ronald, Deridder- Sander & Devroey- Dirk
BACKGROUND: Influenza causes a substantial socioeconomic burden. In Belgium- only 54% of the target group receives an annual vaccination. Patient reminder/recall systems are effective in improving...
Stockwell- Melissa S, Westhoff- Carolyn, Kharbanda- Elyse Olshen, Vargas- Celibell Y, Camargo- Stewin, Vawdrey- David K & Casta {n}o- Paula M
OBJECTIVES: We evaluated the impact of influenza vaccine text message reminders in a low-income obstetric population. METHODS: We conducted a randomized controlled trial that enrolled 1187 obstetric...
Szilagyi- P G, Rodewald- L E, Savageau- J, Yoos- L & Doane- C
Fewer than 10% of children with moderate or severe asthma receive an annual influenza vaccination despite their heightened susceptibility to severe infections and recommendations by the American...
Pierson- Rebecca C, Malone- Anita M & Haas- David M
Influenza infection is the cause of thousands of hospitalizations and deaths each year/ infection during pregnancy results in increased morbidity and mortality. Underserved women are particularly...
Hofstetter- Annika M, Vargas- Celibell Y, Camargo- Stewin, Holleran- Stephen, Vawdrey- David K, Kharbanda- Elyse Olshen & Stockwell- Melissa S
BACKGROUND: Influenza vaccination coverage is low- especially among low-income populations. Most doses are generally administered early in the influenza season- yet sustained vaccination efforts are...
A. Russell Localio, Alexander G. Fiks, Anthony A. Luberti, Evaline A. Alessandrini, Kenya F. Hunter, Louis M. Bell, Robert W. Grundmeier, Tyra Bryant-Stephens
OBJECTIVE: The goal was to assess the impact of influenza vaccine clinical alerts on missed opportunities for vaccination and on overall influenza immunization rates for children and adolescents with...
Clark- Sarah J, Lamarand- Kara & Dombkowski- Kevin J
CONTEXT: Children with chronic medical conditions are at increased risk of complications from influenza- yet their vaccination rates are low. The Michigan Care Improvement Registry (MCIR)- a...
Daley- Matthew F, Barrow- Jennifer, Pearson- Kellyn, Crane- Lori A, Gao- Dexiang, Stevenson- John M, Berman- Stephen & Kempe- Allison
OBJECTIVES: Despite long-standing recommendations to provide annual influenza vaccination to children with chronic medical conditions- immunization rates are <10% in most primary care settings. Many...
Kharbanda- Elyse Olshen
Pregnant women and children are at increased risk of severe influenza infections. Despite existing recommendations- uptake of influenza vaccine in these vulnerable groups remains low. Text message...
Esposito- Susanna, Pelucchi- Claudio, Tel- Francesca, Chiarelli- Gabriella, Sabatini- Caterina, Semino- Margherita, Marseglia- Gian Luigi, De Mattia- Domenico & Principi- Nicola
In order to verify whether a telephone recall system directly managed by pediatricians who usually follow up children for their asthma is more effective than an anonymous recall system- we randomly...
Birmingham- Eileen, Catallozzi- Marina, Findley- Sally E, Vawdrey- David K, Kukafka- Rita & Stockwell- Melissa S
OBJECTIVE: To explore pediatric providers' perceived barriers to influenza vaccine delivery- and desired characteristics and potential concerns regarding an influenza vaccine alert integrated into...
Pereira- Jennifer A, Quach- Susan, Hamid- Jemila S, Heidebrecht- Christine L, Quan- Sherman D, Nassif- Jane, Diniz- Amanda Jane, Van Exan- Robert, Malawski- Jeffrey, Gentry- Adrian, Finkelstein- Michael, Guay- Maryse, Buckeridge- David L, Bettinger- Julie A, Kalailieff- Donna & Kwong- Jeffrey C
BACKGROUND: In response to the need for improved quality of vaccine inventory and client immunization records- barcodes containing a unique identifier and lot number will be placed on all vaccine...
Quan- Kathleen A., Cousins- Sarah M., Hizon- Denise A., Heck- Kristie K., Samuelson- Pamela, Garcia- Froylan & Huang- Susan S.
In implementing a hospital mandatory influenza vaccination policy, we developed an automated, real-time tracking and reminder system. Of 6,957 policy-covered individuals automatically identified,...
Charles T. Allred, Rick D. Kellerman, Larry E. Frisch
OBJECTIVE: To determine if postcard and telephone reminders increased the rate of influenza immunization of Medicare beneficiaries. DESIGN: Before and after trial (postcard reminders) with...
Stockwell- Melissa S., Kharbanda- Elyse Olshen, Martinez- Raquel Andres, Vargas- Celibell Y., Vawdrey- David K. & Camargo- Stewin
CONTEXT: Influenza infection results in substantial costs- morbidity- and mortality. Vaccination against influenza is particularly important in children and adolescents who are a significant source...
Richard Pebody, Fateha Begum, Karen Noakes, Peter Gates, David Salisbury
This paper describes a web-based system developed to collect data on influenza (flu) vaccine uptake in near real time during the flu season in England. Data are collected from all GP practices...