Tanzania's Roll Out Plan identifies responsible EPI person and technical partner, deliverables, and timeline for main HPV vaccine introduction activities.
HPV vaccine introduction training and microplanning slides. HPV vaccine and IPV introduction training were combined as they were being introduced simultaneously. The slide decks included are those...
The 42nd Global Advisory Committee on Vaccine Safety (GACVS) virtual meeting in May 2020 addressed pharmacovigilance preparedness for the launch of the future COVID-19 vaccines. One of their...
To support national immunization programme managers to optimize the introduction and implementation of influenza immunization programmes in countries, WHO has developed the Influenza Post...
The WHO vaccine market intelligence database
compiles vaccine purchase (product, price and procurement) data as reported by countries via the WHO/UNICEF Joint Reporting Form (JRF) over the
period...
This study provides the most updated understanding of current and future global trends and drivers of supply and demand for HPV vaccine. It also identifies actions to help address the current and...
This document brings together a range of resources to provide an overview of the global policies, potential interventions and strategies related to the integration of immunization services. It also...
The human papillomavirus (HPV) vaccination school-based programme for girls aged 12–13 years began in Ireland in 2010. Initially, the proportion of students who completed the vaccination course was...
This essential resource document reviews the principles and issues to be considered when making decisions about planning and implementing the introduction of a vaccine into a national immunization...
With the previous edition of Immunization in Practice (IIP) having been translated and used throughout the world, we realized the tremendous responsibility we had when we embarked on this new...
This Facts Sheet informs of the availability of Measles vaccine and combined Measles-Rubella (MR) vaccine in both a 10-dose vial and a 5-dose vial presentations through (or via) UNICEF procurement.
Vaccination with Human Papillomavirus (HPV) vaccine is recommended for 11–12 years-old, but uptake is suboptimal. Current messaging focuses on HPV infection transmission and prevention. Parents...
Shanchol™, a WHO-prequalified oral cholera vaccine (OCV), has been used to control endemic cholera in Asia, as well as in emergencies and outbreaks elsewhere. The vaccine has not been used by...
Live oral rotavirus (RV) vaccines used worldwide are most effective in reducing diarrheal hospitalizations from RV in high income countries and least effective in low income countries where RV...
To summarize and critically evaluate the evidence on the impact and effectiveness of meningococcal vaccination programs around the world in order to inform decision-making in Latin America and the...
Three highly effective vaccines are available to prevent human papillomavirus (HPV) infection, and they have been introduced in many countries around the world. This article describes advances and...
Anika Singanayagam, Maria Zambon, Ajit Lalvani, Wendy Barclay
Conflicting reports have emerged about the effectiveness of the live attenuated influenza vaccine. The live attenuated influenza vaccine appears to protect particularly poorly against currently...
Background: Due to competing health priorities and limited resources, many low-income countries, even those with a high disease burden, are not able to introduce pneumococcal conjugate vaccines....
Infections due to hepatitis B virus (HBV) are a leading cause of death worldwide. WHO estimated that in 2015, 257 million people globally were living with chronic HBV infection and that 887 000...
Objective To describe the implementation and feasibility of an innovative mass vaccination strategy – based on single-dose oral cholera
vaccine – to curb a cholera epidemic in a large urban...
BACKGROUND: In 2016, the response to a yellow fever outbreak in Angola and the Democratic Republic of Congo led to a global shortage of yellow fever vaccine. As a result, a fractional dose of the...
Due to their thermosensitivity, most vaccines must be kept refrigerated from production to use. To successfully carry out global immunization programs, ensuring the stability of vaccines is crucial....
A clear vision for vaccines research and development (R&D) is needed if Europe is to continue to lead the discovery of next generation vaccines. Innovation Partnership for a Roadmap on Vaccines in...
Background: A safe, effective, and rapidly scalable vaccine against Zika virus infection is needed. We developed a purified formalin-inactivated Zika virus vaccine (ZPIV) candidate that showed...
Background: The Zika virus epidemic and associated congenital infections have prompted rapid vaccine development. We assessed two new DNA vaccines expressing premembrane and envelope Zika virus...
Objective: The objective was to investigate how state level strategies in South Carolina could maximize HPV vaccine uptake. Design: An environmental scan identified barriers, facilitators, and...
This field guide prepares you to conduct qualitative formative research using focus group discussions and individual in-depth interviews. The insights you gather about your audience will help you...
In 1796, Edward Jenner developed the smallpox vaccine consisting of pustular material obtained from lesions on cows affected by so-called cow-pox. The disease, caused by cowpox virus, confers...
BACKGROUND: Rotavirus vaccines are less effective in developing countries versus developed countries. One hypothesis for this difference in performance is that higher levels of maternal antibodies in...
Background: To inform national healthcare authorities whether quadrivalent influenza vaccines (QIVs) provide better value for money than trivalent influenza vaccines (TIVs), we assessed the...
Each year, IVAC prepares the Pneumonia and Diarrhea Progress Report and publishes it for World Pneumonia Day on November 12. The report evaluates the annual progress made in prevention and control of...
Although effective rabies virus vaccines have been existing for decades, each year, rabies virus infections still cause around 50.000 fatalities worldwide. Most of these cases occur in developing...
Background: Strategies are needed to improve oral rotavirus vaccine (RV), which provides sub-optimal protection in developing countries. Probiotics and zinc supplementation could improve RV...
Following publication of results from two phase-3 clinical trials in 10 countries or territories, endemic countries began licensing the first dengue vaccine in 2015. Using a published mathematical...
New vaccines designed to prevent diseases endemic in low and middle-income countries are being introduced without prior utilization in countries with robust vaccine pharmacovigilance systems. Our aim...
Background: In Quebec, 7-valent (PCV7), 10-valent (PCV10) and 13-valent (PCV13) pneumococcal conjugate vaccines were successively used for the immunization of children according to a 2+1 doses...
A reactive campaign using two doses of Shanchol Oral Cholera Vaccine (OCV) was implemented in 2016 in the Lake Chilwa Region (Malawi) targeting fish dependent communities. Three strategies for the...
Background: Rotavirus is a highly contagious virus causing gastroenteritis, mostly in children under the age of 5. Since 2006, two vaccines are available in Germany. In 2013, these were included into...
Background: On Sept 1, 2008, Scotland launched routine vaccination for human papillomavirus (HPV) types 16 and 18, targeted at 12–13-year-old girls, of whom 92·4% were fully vaccinated in...
Monovalent Hepatitis B vaccine (HepB) is heat stable, making it suitable for storage outside cold chain (OCC) at 37 °C for 1 month. We conducted an OCC project in the Solomon Islands to determine...
Rotavirus is a leading cause of severe pediatric diarrhea globally, estimated to have caused 120,000 deaths among
children aged <5 years in sub-Saharan Africa in 2013 (1). In 2009, the World Health...
Capable of inducing antigen-specific immune responses in both systemic and mucosal compartments without the use of syringe and needle, mucosal vaccination is considered ideal for the global control...
As companies, countries, and governments consider investments in vaccine production for routine immunization and outbreak response, understanding the complexity and cost drivers associated with...
The sexually transmitted infection gonorrhoea is a global public health problem for which no vaccine is available. More than 106 million new cases of gonorrhoea are estimated to occur yearly...
Azwifarwi Mudau, Susan A Nzenze, Fatima Solomon, Cynthia G Whitney, Katherine L O’Brien, Elizabeth Zell, Shabir A Madhi, Michelle Groome, Jennifer Verani, Alane Izu
Among children younger than five years, Streptococcus pneumoniae is the leading cause of bacterial pneumonia and such pneumonia caused an estimated 411 000 deaths in 2010 and 335 000 deaths in 2015...
Recommendations on the use of HPV vaccines were issued by the WHO Strategic Advisory Group of Experts (SAGE) on Immunization at its meeting in April 2022, and subsequently endorsed by WHO.
This...
Rotavirus is the most common cause of moderate-to-severe infant diarrhoea in developing countries, resulting in enormous morbidity, mortality, and economic burden. A bovine-human reassortant...
Inadvertent vaccine freezing often occurs in the cold chain and may cause damage to freeze‑sensitive vaccines. Liquid vaccines that contain aluminum salt adjuvants are particularly vulnerable....
Introducing a new vaccine is a large-scale endeavor that can face many challenges, resulting in introduction delays and inefficiencies. The development of national task teams and tools, such as...
Background: Kano State, Nigeria, introduced inactivated polio vaccine (IPV) into its routine immunization (RI) schedule in March 2015 and was the pilot site for an RI data module for the National...
Background: HPV vaccination uptake in boys is suboptimal in many jurisdictions, particularly in the absence of publicly funded HPV vaccination programs. Parents represent key decision-makers of HPV...
The number of vaccines available to low-income countries has increased dramatically over the last decade. Overall infant immunization coverage in the WHO African region has stagnated in the past few...
Katja HöschlerEmail the author Katja Höschler & Maria C Zambon
Despite strong recommendations, influenza vaccine uptake data for the UK for 2015–16 show that actual uptake in the population targeted lags behind the goal of the national vaccine programme,1...
Hepatitis B is highly endemic in the Republic of Kiribati, while the coverage of timely birth dose vaccination, the primary method shown to prevent mother-to-child transmission of hepatitis B virus,...
In 2013, the Council for International Organizations of Medical Sciences (CIOMS) created a Working Group on Vaccine Safety (WG) to address unmet needs in the area of vaccine pharmacovigilance....
As of May 2017, two medical laboratory scientists employed by the Sokoto State Government, jointly trained by the University of Nebraska Medical Centre and eHA are operating the lab. During the 2017...
In South Africa, HPV vaccination programme has been incorporated recently in the school health system. Since doctors are the most trusted people regarding health issues in general, their knowledge...
Keith P Klugman, Sharon Bergquist, Ajoke Sobanjo-ter Meulen
Although considerable progress has been made globally to reduce under-5 mortality, advances in the reduction of neonatal deaths in the first year of life have been slower. The annual deaths of almost...
Pneumococcal conjugate vaccines have proven highly effective in decreasing invasive disease and pneumonia in young children. However, there is considerable geographic variability in the impact of...
In 1997, Milstien, Batson, and Meaney published “A Systematic Method for Evaluating the Potential Viability of Local Vaccine Producers.” The paper identified characteristics of successful vaccine...
As countries expand immunisation programmes to include new vaccines and ensure increased coverage and equity, existing and potential constraints exist within the supply chain systems to manage an...
Objective: To synthesise lessons learnt and determinants of success from human papillomavirus (HPV) vaccine demonstration projects and national programmes in low- and middle-income countries...
This fact sheet describes the work and approach of the Typhoid Vaccine Acceleration Consortium (TyVAC), a partnership between the Center for Vaccine Development at the University of Maryland, the...
This fact sheet describes PATH’s efforts to eliminate meningococcal meningitis epidemics from Africa, once and for all. It covers work across meningitis projects, including the development and...
Background: In preparation for the introduction of MenAfriVac, a meningococcal group A conjugate vaccine developed for the African meningitis belt, an enhanced meningitis surveillance network was...
Background: West Nile virus (WNV) is the leading cause of domestically-acquired arboviral disease in the United States. Several WNV vaccines are in various stages of development. We estimate the...
Background: In children, the 13 and 10-valent pneumoccocal conjugate vaccines (PCV13/10) are currently approved for the prevention of invasive pneumococcal disease (IPD). Acceptability is a key...
Background: Pregnancy increases the risk of harmful effects from cholera for both mothers and their fetuses. A killed oral cholera vaccine, Shanchol (Shantha Biotechnics, Hydrabad, India), can...
Objective: At the end of 2013, a pilot experiment was carried out in Comé health zone (HZ) in an attempt to optimize the vaccine supply chain. Four commune vaccine storage facilities were replaced...