Immunogenicity of a human rotavirus vaccine (RIX4414) after storage at 37°C for seven days

Author: Kerdpanich A et al.

Abstract

The lyophilized formulation of the human rotavirus vaccine, RIX4414 (Rotarix™), is recommended to be stored at 2°C-8°C for optimal immunogenicity. In some settings with inadequate infrastructure for vaccine storage, unforeseen circumstances may cause cold chain breakage, resulting in the vaccine to be left at ambient temperatures. This study evaluated the heat stability of lyophilized RIX4414 vaccine in terms of immunogenicity when stored at tropical room temperature (37°C) for 7 days before reconstitution.

About

Type Journal article
Language English
Country Not Specified
Link http://www.ncbi.nlm.nih.gov/pubmed/21228629
Journal Hum Vaccin.
Volume 7
Year 2011
Disease Rotavirus
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Added on 24 November 2015 06:44:21
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