A randomized clinical trial in adults and newborns in South Africa to compare the safety and immunogenicity of bacille Calmette-Guérin (BCG) vaccine administration via a disposable-syringe jet injector to conventional technique with needle and syringe

Author: Hennie D. Geldenhuys, Helen Mearns, Jennifer Foster, Eugene Saxon, Benjamin Kagina, Laura Saganic, Courtney Jarrahian, Michele D. Tameris, One B. Dintwe, Michele Van Rooyen, Kany-Kany A. Luabeya, Gregory Hussey, Thomas J. Scriba, Mark Hatherill, and Darin Zehrung


Intradermal bacille Calmette-Guérin (BCG) vaccination by needle-free, disposable-syringe jet injectors (DSJI) is an alternative to the Mantoux method using needle and syringe (NS). We compared the safety and immunogenicity of BCG administration via the DSJI and NS techniques in adults and newborn infants at the South African Tuberculosis Vaccine Initiative (SATVI) research site in South Africa.


Type Journal article
Language English
Country Not Specified
Link https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564069/
Journal Vaccine
Volume 33
Publisher Elsevier
Disease , BCG , Delivery Technology , disposable-syringe jet injectors , needle-free , Tuberculosis
Added by Marilyn Kelly
Added on 22 February 2017 14:38:50
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