Generic protocol for monitoring impact of rotavirus vaccination on gastroenteritis disease burden and viral strains

Language
Published
2009

This generic protocol outlines a uniform approach to monitoring the impact of rotavirus vaccines that can be modified by countries to meet their specific needs. It provides background and justification for monitoring the impact of rotavirus vaccines once introduced in routine immunization schedules; describes assessment of vaccine impact by monitoring disease trends, using either existing data sources or active surveillance system; explain an approach for assessing vaccine effectiveness using a case control methodology; and describes the monitoring of the distribution of circulating rotavirus strains.