lundi 27 juillet 2009
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In the course of the revision of the WHO Multi-dose Vial Policy (MDVP) we came across the question if there were any vaccines in multidose vials that had to be discarded less than 6 hours after having been opened. Some package inserts seem to indicate this, but it is not clear whether it would deteriorate greatly or become dangerous if aseptic technique was applied and the vaccine kept under proper cold chain and storage conditions. I would be interested if such vaccines existed and what scientific data there is to back the statement. Rudi Eggers
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