mardi 24 février 2015
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In its January 2015 meeting, the WHO Executive Board called on all Member States to accelerate preparation for a globally coordinated switch from trivalent to bivalent OPV in April 2016. The Board’s request follows the WHO SAGE announcement in October 2014 that preparations are on track for this important milestone towards achieving polio eradication. The withdrawal of OPV is a critical step within objective 2 of the Polio Eradication and Endgame Strategic Plan 2013-2018. OPV works by using live attenuated (weakened) polioviruses to stimulate an immune response against three different types of poliovirus (types 1, 2 and 3). Use of OPV has nearly eliminated polio from the planet, with the last case of wild poliovirus type 2 seen in 1999. However, on very rare occasions, in countries where immunization coverage is low, vaccine-derived polioviruses from strains initially contained in OPV can change and spread to others. To counter this potential risk, OPVs will be removed in a phased manner, starting with the replacement of trivalent OPV with bivalent OPV, the latter protecting against types 1 and 3. The introduction of IPV will also help to manage risks associated with the withdrawal of the type 2 component of trivalent OPV, and help to boost immunity to types 1 and 3. In each country, the switch is expected to occur within a two-week period. Preparations for the switch will affect every stage of the supply chain from procurement to delivery to disposal. In anticipation of the switch, TechNet subscribers are encouraged to read and familiarize themselves with the rationale for, timing, and logistical implications of this important stage in polio eradication. WHO will continue posting information about the switch on TechNet and through other relevant channels and will be available to answer questions and address issues as they arise. To learn more about the switch and access all available materials, please visit: http://www.who.int/immunization/diseases/poliomyelitis/endgame_objective2/en/ For more information, please visit our website or send an email to: [email protected]
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