Sample design and procedures for Hepatitis B immunization surveys: A companion to the WHO cluster survey reference manual

This document is designed to supplement the sample design, sample selection and sample size determination guidance provided by the World Health Organization (WHO) documents, “Immunization Cluster Survey Reference Manual” (WHO, 2005) and “Assessing the impact of Hepatitis B vaccination: Strategies and overview of issues” (WHO, 2006). This report is written as an aid to researchers and health professionals who are preparing to conduct a Hepatitis B vaccination program impact assessment or HBV sero-prevalence survey. The discussion emphasizes practical issues related to sample design choice, sample selection methods and procedures for minimizing both sampling and no sampling errors in the survey data.