Journal article
The immunological effects of oral polio vaccine provided with BCG vaccine at birth: A randomised trial
Vaccines may have non-specific effects. An observational study from Guinea-Bissau suggested that oral polio vaccine at birth (OPV0) provided with Bacillus Calmette–Guérin (BCG) vaccine was associated with down-regulation of the immune response to BCG vaccine 6 weeks later. Based on the previous finding, we wanted to test our a priori hypothesis that OPV would dampen the immune response to BCG, and secondarily to test immune responses to other antigens.
Authors
Languages
- English
Publication year
2014
Journal
Vaccine
Volume
45
Type
Journal article
Categories
- Service delivery
Diseases
- Polio
Countries
- Guinea Bissau
Tags
- OPV
WHO Regions
- African Region