An in-depth overview of the implementation research conducted in Zambia. The following outline some key results: • The household coverage survey found a statistically significant increase in coverage for both doses. Wastage also decreased statistically significantly in health facilities where 5-dose MR vials were used. • When using 5-dose vials, healthcare workers frequently reported that they believe they can reach more children. • An analysis of cold chain equipment in intervention health facilities showed that there was sufficient space to accommodate the small increase in volume that occurred when switching from 10-dose to 5-dose MR vaccine vials. • The incremental annual costs for switching to 5-dose vials (excluding the value of vaccines) was $0.11.