Economic Review of Immunization Information Systems to Increase Vaccination Rates: A Community Guide Systematic Review.

CONTEXT:: A recent systematic review found that use of an immunization information system (IIS) is an effective intervention to increase vaccination rates. The purpose of this review was to evaluate costs and benefits associated with implementing- operating- and participating with an IIS. The speed of technology change has had an effect on costs and benefits of IIS and is considered in this review. EVIDENCE ACQUISITION:: An economic evaluation for IIS was conducted using methods developed for Community Guide systematic reviews. The literature search covered the period from January 1994 to March 2012 and identified 12 published articles and 2 government reports. EVIDENCE SYNTHESIS:: Most studies involving cost data evaluated (1) system costs of building an IIS and (2) cost of exchanging immunization data/ most economic benefits focused on administrative efficiency. CONCLUSIONS:: A major challenge to evaluating a technology-based intervention is the evolution that comes with technology improvements and advancem