Control of HPV-associated cancers with HPV vaccination

In the Lancet Infectious Diseases, Eric Chow and colleagues1 present evidence of remarkable population effectiveness against human papillomavirus (HPV), with virtual eradication of targeted types, among heterosexual men within a few years after vaccination of the young Australian female population with the quadrivalent HPV vaccine (4vHPV). Their study is notable because of its inventive observational methods and compelling implications.