Article de revue
Identification and control of a poliomyelitis outbreak in Xinjiang, China
Between July 3 and October 9, 2011, investigators identified 21 cases of infection with wild-type poliovirus and 23 clinically compatible cases in southern Xinjiang. Wild-type poliovirus type 1 was isolated from 14 of 673 contacts of patients with acute flaccid paralysis (2.1%) and from 13 of 491 healthy persons who were not in contact with affected persons (2.6%). Sequence analysis implicated an imported wild-type poliovirus that originated in Pakistan as the cause of the outbreak. A public health emergency was declared in Xinjiang after the outbreak was confirmed. Surveillance for acute flaccid paralysis was enhanced, with daily reporting from all public and private hospitals. Five rounds of vaccination with live, attenuated oral poliovirus vaccine (OPV) were conducted among children and adults, and 43 million doses of OPV were administered. Trivalent OPV was used in three rounds, and monovalent OPV type 1 was used in two rounds. The outbreak was stopped 1.5 months after laboratory confirmation of the index case.
Auteurs
Langues
- Anglais
Année de publication
2013
Journal
N Engl J Med
Volume
369
Type
Article de revue
Catégories
- Prestation de services
Maladies
- Polio
Pays
- Chine
Organisations
- Organisation Mondiale de la Santé (OMS)
Mots-clés
- Épidémie
Régions de l'OMS
- Région du Pacifique occidental
