Article de revue
Immune responses after fractional doses of inactivated poliovirus vaccine using newly developed intradermal jet injectors: A randomized controlled trial in Cuba
The World Health Organization recommends that, as part of the new polio endgame, a dose of inactivated poliovirus vaccine (IPV) be introduced by the end of 2015 in all countries using only oral poliovirus vaccine (OPV). Administration of fractional dose (1/5th of full dose) IPV (fIPV) intradermally may reduce costs, but its administration is cumbersome with BCG needle and syringe. We evaluated performance of two newly developed intradermal-only jet injectors and compared the immune response induced by fIPV with that induced by full-dose IPV.
Auteurs
Langues
- Anglais
Année de publication
2014
Éditeur
Elsevier
Journal
Vaccine
Volume
2
Type
Article de revue
Catégories
- Vaccins et dispositifs d'administration
Maladies
- Polio
Mots-clés
- Delivery device