BACKGROUND: Immunization coverage remains low- particularly in low- and middle-income countries (LMIC)- despite its proven effectiveness in reducing the burden of childhood infectious diseases. A Cochrane review has shown that patient reminder recall is effective in improving coverage of immunization but technologies to support this strategy are lacking in LMIC. OBJECTIVES: To evaluate the effectiveness of intervention strategies to boost and sustain high childhood immunization coverage in LMIC. SEARCH STRATEGY: We searched the following databases for primary studies: Cochrane Central Register of Controlled Trials (CENTRAL) 2010- Issue 1- part of The Cochrane Library. www.thecochranelibrary.com- including the Cochrane Effective Practice and Organisation of Care (EPOC) Group Specialised Register (searched 8 July 2010)/ MEDLINE- Ovid (1948 to March Week 3 2011) (searched 30 March 2011)/ EMBASE- Ovid (1980 to 2010 Week 26) (searched 8 July 2010)/ CINAHL- EBSCO (1981 to present ) (searched 8 July 2010)/ LILACS- V