Article de revue

Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial

BCG vaccination provides incomplete protection against tuberculosis in infants. A new vaccine, modified Vaccinia Ankara virus expressing antigen 85A (MVA85A), was designed to enhance the protective efficacy of BCG. The study aimed to assess safety, immunogenicity, and efficacy of MVA85A against tuberculosis and Mycobacterium tuberculosis infection in infants.

Langues

  • Anglais

Année de publication

2013

Journal

Lancet

Volume

9871

Type

Article de revue

Catégories

  • Vaccins et dispositifs d'administration

Maladies

  • Tuberculose

Pays

  • Afrique du Sud

Mots-clés

  • Suivi de la couverture
  • Introduction de nouveaux vaccins

Régions de l'OMS

  • Région africaine

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