This guidance provides a framework and recommended actions for countries to: develop, assess, and update a detailed NDVP to deploy pandemic vaccines and other ancillary products within seven days to permit rapid vaccination of the target population; identify vaccination strategies and operational gaps and plan for surge capacity during a pandemic to deploy and vaccinate the target population quickly; establish a uniform management structure, command and control protocol as well as effective coordination, information management, and communication between all sectors of government, private, and civil society through which the vaccine will be deployed; develop micro-plans and standard operating procedures for the deployment and vaccination activities and prioritize actions on when to implement each and how to coordinate them; enhance or establish a post-deployment surveillance system; mobilize resources to support all activities related to deployment and vaccination; and exercise and test the NDVP over time to address changes in policies and technology.