Global Manual on Surveillance of Adverse Events Following Immunization

Monitoring of adverse events following immunization (AEFI) is an essential strategy for ensuring the safety of vaccines. This new manual provides guidance on setting-up AEFI surveillance systems with standardized methodologies and tools. It addresses the investigation of AEFI, how to analyze surveillance data, causality assessment and how to respond to serious AEFI, including communication. It also includes a description of the most common vaccine reactions provides references to the most recent references in vaccine pharmacovigilance.

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