This document has been developed following extensive consultations and consideration of key references. It summarizes immunological and epidemiological information on targeted vaccinepreventable diseases of public health importance in Kenya (including those in the EPI schedule) and presents recommendations on priority vaccines for Kenya, including vaccination schedules. It provides technical reference and guidelines for frontline health workers who are involved in managing and monitoring Immunization service delivery at all levels of the health care system. The Kenya National Immunization Policy Guidelines have been developed in line with the Constitution of Kenya 2010, the Kenya Vision 2030 and the Kenya Health Policy 2014–2030. It is also aligned with Immunization Agenda 2030, the WHO Regional Immunization Strategic Plan for Africa, and the Addis Ababa Declaration on Immunization.