Manual needle removers (hereafter referred to as needle removers) are used by injection providers to separate the hub and needle from the syringe. Needle removers immediately isolate the contaminated sharp and disable the syringe. The process results in two waste streams: the contained needles (sharps) and the “defanged,” disabled syringes. Needle removers are used to reduce the risk of potential infection to patients, health care workers, waste handlers, and the community through safer waste-disposal systems.