POST 01118E : ORAL POLIO VACCINE COLOUR
Follow-up on Post 01050E, 01058E, 01100E and 01107E
8 July 2007
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No other comment or reply were received on this topic. Thus [log in to unmask]">Jacqueline Fournier-[log in to unmask]">Caruana, [log in to unmask]">Hans [log in to unmask]">Everts and [log in to unmask]">Diana Chang[log in to unmask]"> Blanc jointly reiterate WHO's position.
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1) Colour variations have no impact on vaccine effectiveness. Colour is not an indicator of quality.
2) All OPV vaccines are supplied by pre-qualified producers and are approved by National Regulatory Authorities.
Phenol red is a residue of vaccine production, that is a visual indicator of the correct cell multiplication, or their degeneration. Some producers, not all, add more in the formulation of the final product for the vaccine to have this pink colour that everybody knows. It happens that this colour turns yellow ; it is a well-known event, rare however
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