POST 00684E : APPROACHES TO ELIMINATING FREEZING : A STUDY REPORT 9 June 2004
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Carib Nelson (mailto:[email protected]) informs us of a study done at PATH.
The full document "Approaches to Eliminating Freezing in Vaccine
Carriers—Testing Report Summary—" can be downloaded from
http://www.technet21.org/pdf_file/ltrp23340.pdf
Size : 950KB
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Here is a study done by Lisa Tam and Jesse Schubert at PATH that could be
interesting for TechNet readers. It looks at the problem of freezing in
vaccine carriers and evaluates several solutions. An abstract follows.
Carib
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ABSTRACT
Freezing of tetanus toxoid (TT), diptheria-pertussis-tetanus (DPT), and
hepatitis B vaccines can cause a loss of vaccine potency. Recent
temperature studies have shown a significant amount of vaccine freezing
during vaccine transport.
In this laboratory study, the extent of freezing in vaccine carriers is
quantified and several options for reducing vaccine freezing are explored.
Freeze prevention methods included ice pack conditioning, water and ice
packs used together, insulation barriers inserted within the vaccine
carrier, cold-absorbing layers placed within the vaccine carrier, and use
of phase change materials as ice packs or barriers.
The simplest solutions offered the best combination of prevention of
freezing, low cost, and minimal loss of cold life. Ice-pack conditioning
and use of half ice-packs/half water-packs were successful strategies.
Insulation and cold-absorption methods were less effective and more
complicated. Any solution to eliminate freezing of vaccines will require
training to increase awareness of the freezing problem and to implement
revised operating procedures.
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