Article de revue

Changes in childhood pneumonia hospitalizations by race and sex associated with pneumococcal conjugate vaccines

ntroduction of the 7-valent pneumococcal conjugate vaccine (PCV7) into the childhood immunization schedule was associated with substantial reductions in invasive pneumococcal disease (IPD) and pneumonia in young children in the United States and elsewhere (1–4). In the United States specifically, black children traditionally had higher IPD and pneumonia rates than white children. However, this racial disparity in IPD was reduced after introduction of PCV7 (5). After the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) in 2010, IPD and pneumonia hospitalizations among children <5 years of age were reduced further, and racial differences in IPD reached an historic low (2,6,7). However, the effect of PCVs on racial disparities for pneumonia, which is much more common than IPD, remains unclear. Furthermore, sex seems to persist as an independent risk factor for IPD after PCV7 introduction (8).

Langues

  • Anglais

Année de publication

2016

Journal

http://wwwnc.cdc.gov/eid/article/22/6/15-2023_article

Volume

6

Type

Article de revue

Catégories

  • Prestation de services

Maladies

  • Infection à pneumocoque

Pays

  • États-Unis

Mots-clés

  • Suivi de la couverture
  • Introduction de nouveaux vaccins

Régions de l'OMS

  • Région des Amériques