Journal article

Changes in childhood pneumonia hospitalizations by race and sex associated with pneumococcal conjugate vaccines

ntroduction of the 7-valent pneumococcal conjugate vaccine (PCV7) into the childhood immunization schedule was associated with substantial reductions in invasive pneumococcal disease (IPD) and pneumonia in young children in the United States and elsewhere (1–4). In the United States specifically, black children traditionally had higher IPD and pneumonia rates than white children. However, this racial disparity in IPD was reduced after introduction of PCV7 (5). After the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) in 2010, IPD and pneumonia hospitalizations among children <5 years of age were reduced further, and racial differences in IPD reached an historic low (2,6,7). However, the effect of PCVs on racial disparities for pneumonia, which is much more common than IPD, remains unclear. Furthermore, sex seems to persist as an independent risk factor for IPD after PCV7 introduction (8).

Languages

  • English

Publication year

2016

Journal

http://wwwnc.cdc.gov/eid/article/22/6/15-2023_article

Volume

6

Type

Journal article

Categories

  • Service delivery

Diseases

  • Pneumococcal disease

Countries

  • United States of America

Tags

  • Coverage monitoring
  • New vaccine introduction

WHO Regions

  • Region of the Americas