Article de revue

Comparing safety & immunogenicity of TB vaccine MVA85A through intramuscular and intradermal routes

Joel Meyer, Stephanie A. Harris, Iman Satti, Ian D. Poulton, Hazel C. Poyntz, Rachel Tanner, Rosalind Rowland, Kristin L. Griffiths, Helen A. Fletcher, Helen McShane

New vaccines to prevent tuberculosis are urgently needed. MVA85A is a novel viral vector TB vaccine candidate designed to boost BCG-induced immunity when delivered intradermally. To date, intramuscular delivery has not been evaluated. Skin and muscle have distinct anatomical and immunological properties which could impact upon vaccine-mediated cellular immunity.

 

Auteurs

Langues

  • Anglais

Année de publication

2013

Journal

Vaccine

Volume

31

Numéro

7

Type

Article de revue

Catégories

  • Vaccins et dispositifs d'administration

Maladies

  • Tuberculose

Mots-clés

  • Dispositif d'administration
  • Introduction de nouveaux vaccins

Ajouté par: Moderator

Ajouté le: 2015-10-26 04:41:51

Consultations: 1704

Liens

URL PubMED

http://www.ncbi.nlm.nih.gov/pubmed/23266342

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