Journal article

Comparing safety & immunogenicity of TB vaccine MVA85A through intramuscular and intradermal routes

Joel Meyer, Stephanie A. Harris, Iman Satti, Ian D. Poulton, Hazel C. Poyntz, Rachel Tanner, Rosalind Rowland, Kristin L. Griffiths, Helen A. Fletcher, Helen McShane

New vaccines to prevent tuberculosis are urgently needed. MVA85A is a novel viral vector TB vaccine candidate designed to boost BCG-induced immunity when delivered intradermally. To date, intramuscular delivery has not been evaluated. Skin and muscle have distinct anatomical and immunological properties which could impact upon vaccine-mediated cellular immunity.

 

Authors

Languages

  • English

Publication year

2013

Journal

Vaccine

Volume

31

Issue

7

Type

Journal article

Categories

  • Vaccines & delivery devices

Diseases

  • TB

Tags

  • Delivery device
  • New vaccine introduction

Added by: Moderator

Added on: 2015-10-26 04:41:51

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Links

PubMED URL

http://www.ncbi.nlm.nih.gov/pubmed/23266342

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