Article de revue
Tuberculosis vaccines – rethinking the current paradigm
Highlights: •Protection can be improved by supplementing instead of boosting BCG immune responses. •T cell responses not detectable by IFN-γ assays can enhance TB control. •Improving central memory T cell responses by vaccines prolongs TB control. •TB virulence and latency antigens missing from BCG improve vaccine effect.
•Vaccine-induced Th17 responses enhance early control of TB.
Auteurs
Langues
- Anglais
Année de publication
2014
Journal
Trends in Immunology
Volume
8
Type
Article de revue
Catégories
- Vaccins et dispositifs d'administration
Mots-clés
- Introduction de nouveaux vaccins
