Article de revue

Vaccine vial monitor availability and use in low- and middle-income countries: A systematic review

Introduction: The vaccine vial monitor (VVM) registers cumulative heat exposure on vaccines over time. As low- and lower-middle-income countries transition beyond support from the Global Alliance for Vaccines and Immunization (Gavi), they will assume full responsibility for vaccine financing and procurement. It is unclear to what extent countries transitioning out of Gavi support will continue to include VVMs on their vaccines. This paper aims to systematically review evidence on VVM availability and use in low- and middle-income countries to document factors behind global access to and country demand for VVMs. Such results could help identify actions needed to ensure continued use of VVMs in countries that transition out of Gavi support. Methods: We performed a systematic review of electronic databases, reference lists, and grey literature in English and French languages with publication dates from 2005 onwards. The studies included were analyzed for the following outcomes: (1) availability and deployment of VVM-labeled vaccines; (2) VVM practices and perceptions in the immunization system; (3) vaccine introduction and decision-making processes; (4) Gavi graduation and vaccine program sustainability. Results: The study found that VVM availability and use was affected by multiple sourcing of vaccines and the extent to which VVM was included in the vaccine specification in the tendering documents when procuring vaccines. Knowledge about VVM and its impact on the EPI program was found to be high among health workers as well as decision-makers. However, the study also found that weak capacity in key national institutions such as NRA and NPA might impact on demand for VVM. As countries take decisions regarding the adoption of new vaccines, factors such as disease burden and vaccine price may assume greater importance than vaccine characteristics and presentation. Finally, the study found that countries rely largely on the advice and recommendations from technical partners such as WHO and PAHO. Conclusion: The study concludes that global access to and country demand for VVM are dependent on policy statements and recommendations about VVM by key policy institutions such as WHO and UNICEF. The study also concludes that despite Gavi-eligible countries having access to VVM-labeled vaccines, inclusion is often below 100%. Weak institutional capacity in key national agencies such as NRA and NPA seems to be a contributing factor, while other factors include the procurement of clear national policies on the inclusion of VVM on vaccines, along with the capacity to enforce the policy. Finally, the study concludes that knowledge about VVM and its impact on vaccine program efficiency, safety, and cost is critical for transitioning countries’ continuous demand for VVM.

Langues

  • Anglais

Année de publication

2017

Journal

Vaccine

Volume

17

Type

Article de revue

Catégories

  • Chaîne d'approvisionnement

Organisations

  • Gavi, l'Alliance du vaccin
  • Organisation Mondiale de la Santé (OMS)

Mots-clés

  • Politique et législation
  • PCV

Références sur le sujet

VVM-OTHER

TitreAuteurAnnéeTypeLangue
Cold chain challenges everywhere - Simona ZipurskyEPELA, World Health Organization (WHO)2013GuidanceAnglais
Impact of VVMs on Wastage and Cold Chain Monitoring During NIDs in NepalB. Aylward, G.P. Ojha, J. Andrus, J. luna, M.B. Bista, N. Rajbhandari1998Case studyAnglais
Interpretation of VVM in relation to other temperature monitoring devices - Umit KartogluEPELA, World Health Organization (WHO)2019TrainingAnglais
Last mile - Umit KartogluEPELA, World Health Organization (WHO)2013GuidanceAnglais
The Book of VVM: Yesterday-today-and-tomorrowUmit Kartoglu2020GuidanceAnglais
Using VVM as a stock management toolEPELA, World Health Organization (WHO)2013TrainingAnglais
Vaccine instability in the cold chain: mechanisms, analysis and formulation strategiesKumru OS et al.2014Journal articleAnglais
Vaccine storage and handling practices among routine immunization service providers in a metropolitan city of north-central NigeriaA. G. Salaudeen , H. A. Ameen, M. M. B. Uthman, O. A. Bolarinwa, O. I. Musa, S. A. AderibigbeJournal articleAnglais
Vaccine Vial Monitor (VVM)-based vaccine managementUmit Kartoglu2020PresentationAnglais
Vaccine vial monitor availability and use in low- and middle-income countries: A systematic reviewPär Eriksson et al.2017Journal articleAnglais
Vaccine Vial Monitors Impact Study during 1997 National Immunization Days in TurkeyBirhan Altay, Oya Zeren Afsar1998Case studyAnglais

Ajouté par: Moderator

Ajouté le: 2017-05-03 09:35:16

Consultations: 1978