Article de revue
“Why has this new vaccine come and for what reasons?” key antecedents and questions for acceptance of a future maternal GBS vaccine: Perspectives of pregnant women, lactating women, and community members in Kenya
Group B streptococcus (GBS) is a leading global cause of neonatal sepsis and meningitis, stillbirth, and puerperal sepsis. While intrapartum antibiotic prophylaxis (IAP) is a currently available GBS disease prevention strategy, IAP is programmatically complex to implement, precluding use in low- and middle-income countries. In Kenya, 2% of stillbirths are attributable to GBS infection. Two maternal GBS vaccines are in late-stage clinical development. However, licensure of a maternal GBS vaccine does not translate into reduction of disease. We conducted 28 in-depth interviews with pregnant people, lactating people, and community members across two counties in Kenya to better understand the attitudes and informational needs of primary vaccine beneficiaries. We identified two emerging themes from the data. The first focused on antecedents to maternal GBS vaccine acceptability. The most common antecedents focused on the vaccine’s ability to protect the baby and/or the mother, followed by community sensitization before the vaccine was available. The second key theme focused on questions that would need to be addressed before someone could accept a maternal GBS vaccine. Three key categories of questions were identified, including vaccine safety compared to vaccine benefits, who gets the vaccine, and how the vaccine works. Realizing the potential benefits of a future GBS maternal vaccine will require a multifactorial approach, including ensuring that communities are aware of GBS-related harms as well as the safety and effectiveness of a maternal GBS vaccine. Our study contributes to informing this multifactorial approach by elucidating the attitudes and concerns of key populations.
Langues
- Anglais
Année de publication
2024
Journal
Human Vaccines & Immunotherapeutics
Type
Article de revue
Catégories
- Initiatives mondiales
Références sur le sujet
MIRI-DEMAND
Titre | Auteur | Année | Type | Langue |
---|---|---|---|---|
“Why has this new vaccine come and for what reasons?” key antecedents and questions for acceptance of a future maternal GBS vaccine: Perspectives of pregnant women, lactating women, and community members in Kenya | Rupali J. Limaye, Prachi Singh, Berhaun Fesshaye, Clarice Lee, Jessica Schue, Ruth A. Karron | 2024 | Journal article | Anglais |
A qualitative inquiry in understanding trusted media sources to reduce vaccine hesitancy among Kenyans | Berhaun Fesshaye, Clarice Lee, Alicia M. Paul, Eleonor Zavala, Prachi Singh, Ruth A. Karron, Rupali J. Limaye | 2023 | Journal article | Anglais |
A socio-ecological comparison of the COVID-19 vaccine decision- making processes among pregnant and lactating women: Findings from Kenya and Bangladesh | Prachi Singh, Berhaun Fesshaye, Eleonor Zavala, Clarice Lee, Ruth A. Karron, Rupali J. Limaye | 2023 | Poster/infographic | Anglais |
A socio-ecological exploration to identify factors influencing the COVID-19 vaccine decision-making process among pregnant and lactating women: Findings from Kenya | Rupali J. Limaye, Alicia M. Paul, Rachel Gur-Arie, Eleonor Zavala, Clarice Lee, Berhaun Fesshaye, Prachi Singh, Wincate Njagi, Paul Odila, Paul Munyao, Rosemary Njogu, Stephen Mutwiwa, Lisa Noguchi, Christopher Morgan, Ruth A. Karron | 2022 | Journal article | Anglais |
Characterizing Attitudes Toward Maternal RSV Vaccines Among Pregnant and Lactating Persons in Kenya: Key Considerations for Demand Generation Efforts for Vaccine Acceptance | Rupali J. Limaye, Molly Sauer, Rosemary Njogu, Prachi Singh, Berhaun Fesshaye, Ruth A. Karron | 2023 | Journal article | Anglais |
Conceptualizing the COVID-19 Pandemic: Perspectives of Pregnant and Lactating Women, Male Community Members, and Health Workers in Kenya | Alicia M. Paul, Clarice Lee, Berhaun Fesshaye, Rachel Gur-Arie, Eleonor Zavala, Prachi Singh, Ruth A Karron, Rupali J. Limaye | 2022 | Journal article | Anglais |
COVID-19 vaccine decision-making among pregnant and lactating women in Bangladesh | Rupali J. Limaye, Prachi Singh, Alicia M. Paul, Berhaun Fesshaye, Clarice Lee, Eleonor Zavala, Sydney Wade, Hasmot Ali, Hafizur Rahman, Shirina Akter, Ruth A. Karron, Towfida Jahan Siddiqua | 2023 | Journal article | Anglais |
COVID-19 vaccine eligibility of pregnant and lactating women in Bangladesh: Gap between policy and policy interpretation among policymakers and healthcare workers | Rupali J. Limaye, Berhaun Fesshaye, Prachi Singh, Eleonor Zavala, Shirina Akter, Towfida Jahan Siddiqua, Hafizur Rahman, Hasmot Ali, Ruth A. Karron | 2023 | Journal article | Anglais |
COVID-19 vaccine preferences for pregnant and lactating women in Bangladesh and Kenya: a qualitative study | Jessica L. Schue, Berhaun Fesshaye, Emily Miller, Prachi Singh, Rupali J. Limaye | 2024 | Journal article | Anglais |
Future GBS vaccines: Perspectives from pregnant and lactating people, healthcare providers, community members, and policymakers in Kenya | Berhaun Fesshaye, Prachi Singh, Molly Sauer, Ruth A. Karron, Rupali J. Limaye | 2023 | Poster/infographic | Anglais |
Lack of clear national policy guidance on COVID-19 vaccines influences behaviors in pregnant and lactating women in Kenya | Eleonor Zavala, Berhaun Fesshaye, Clarice Lee, Stephen Mutwiwa, Wincate Njagi, Paul Munyao, Rosemary Njogu, Rachel Gur-Arie, Alicia M. Paul, Taylor A. Holroyd, Prachi Singh, Ruth A. Karron, Rupali J. Limaye | 2022 | Journal article | Anglais |
Lessons learned from COVID-19 vaccine acceptance among pregnant and lactating women from two districts in Kenya to inform demand generation efforts for future maternal RSV vaccines | Rupali J. Limaye, Prachi Singh, Berhaun Fesshaye, Ruth A. Karron | 2024 | Journal article | Anglais |
Maternal Immunization Decision-Making Among Pregnant and Lactating People in Kenya: A Qualitative Exploration of Peer Influences on Vaccine Decision-Making for a Future RSV Vaccine | Prachi Singh, Berhaun Fesshaye, Clarice Lee, Rosemary N. Njogu, Ruth A. Karron, Rupali J. Liimaye | 2024 | Journal article | Anglais |
Maternal Immunization Readiness Initiative (MIRI) Kenya Results Dissemination | Rupali J. Limaye, Berhaun Fesshaye, Prachi Singh, Emily Miller, Ruth A. Karron | 2023 | Poster/infographic | Anglais |
Maternal Immunization Readiness Initiative (MIRI) Kenya Results Dissemination Day 1 Slides | Rupali J. Limaye, Prachi Singh, Berhaun Fesshaye, Eleonor Zavala, Clarice Lee, Ruth A. Karron | 2023 | Presentation | Anglais |
Maternal Immunization Readiness Initiative (MIRI) Kenya Results Dissemination Day 2 Slides | Rupali J. Limaye, Prachi Singh, Berhaun Fesshaye, Eleonor Zavala, Clarice Lee, Ruth A. Karron | 2023 | Presentation | Anglais |
Maternal Immunization Readiness Initiative (MIRI) Kenya Results Dissemination Day 3 Slides | Rupali J. Limaye, Prachi Singh, Berhaun Fesshaye, Eleonor Zavala, Clarice Lee, Ruth A. Karron | 2023 | Presentation | Anglais |
RSV awareness, risk perception, causes, and terms: Perspectives of pregnant and lactating women in Kenya to inform demand generation efforts for maternal RSV vaccines | Rupali J. Limaye, Berhaun Fesshaye, Prachi Singh, Ruth A. Karron | 2023 | Journal article | Anglais |
Sources of COVID-19 Vaccine Promotion for Pregnant and Lactating Women in Bangladesh | Berhaun Fesshaye, Sydney A. Wade, Clarice Lee, Prachi Singh, Eleonor Zavala, Hasmot Ali, Hafizur Rahman, Towfida Jahan Siddiqua, Shirina Akter, Ruth A. Karron, Rupali J. Limaye | 2023 | Journal article | Anglais |
Understanding Kenyan policymakers’ perspectives about the introduction of new maternal vaccines | Rupali J. Limaye, Berhaun Fesshaye, Prachi Singh, Rose Jalango, Rosemary Njrua Njogu, Emily Miller, Jessica Schue, Molly Sauer, Clarice Lee, Ruth A. Karron | 2024 | Journal article | Anglais |