Journal article

“Why has this new vaccine come and for what reasons?” key antecedents and questions for acceptance of a future maternal GBS vaccine: Perspectives of pregnant women, lactating women, and community members in Kenya

Group B streptococcus (GBS) is a leading global cause of neonatal sepsis and meningitis, stillbirth, and puerperal sepsis. While intrapartum antibiotic prophylaxis (IAP) is a currently available GBS disease prevention strategy, IAP is programmatically complex to implement, precluding use in low- and middle-income countries. In Kenya, 2% of stillbirths are attributable to GBS infection. Two maternal GBS vaccines are in late-stage clinical development. However, licensure of a maternal GBS vaccine does not translate into reduction of disease. We conducted 28 in-depth interviews with pregnant people, lactating people, and community members across two counties in Kenya to better understand the attitudes and informational needs of primary vaccine beneficiaries. We identified two emerging themes from the data. The first focused on antecedents to maternal GBS vaccine acceptability. The most common antecedents focused on the vaccine’s ability to protect the baby and/or the mother, followed by community sensitization before the vaccine was available. The second key theme focused on questions that would need to be addressed before someone could accept a maternal GBS vaccine. Three key categories of questions were identified, including vaccine safety compared to vaccine benefits, who gets the vaccine, and how the vaccine works. Realizing the potential benefits of a future GBS maternal vaccine will require a multifactorial approach, including ensuring that communities are aware of GBS-related harms as well as the safety and effectiveness of a maternal GBS vaccine. Our study contributes to informing this multifactorial approach by elucidating the attitudes and concerns of key populations.

Languages

  • English

Publication year

2024

Journal

Human Vaccines & Immunotherapeutics

Type

Journal article

Categories

  • Global initiatives

Topic references

MIRI-DEMAND

TitleAuthorYearTypeLanguage
“Why has this new vaccine come and for what reasons?” key antecedents and questions for acceptance of a future maternal GBS vaccine: Perspectives of pregnant women, lactating women, and community members in KenyaRupali J. Limaye, Prachi Singh, Berhaun Fesshaye, Clarice Lee, Jessica Schue, Ruth A. Karron2024Journal articleEnglish
A qualitative inquiry in understanding trusted media sources to reduce vaccine hesitancy among KenyansBerhaun Fesshaye, Clarice Lee, Alicia M. Paul, Eleonor Zavala, Prachi Singh, Ruth A. Karron, Rupali J. Limaye2023Journal articleEnglish
A socio-ecological comparison of the COVID-19 vaccine decision- making processes among pregnant and lactating women: Findings from Kenya and BangladeshPrachi Singh, Berhaun Fesshaye, Eleonor Zavala, Clarice Lee, Ruth A. Karron, Rupali J. Limaye2023Poster/infographicEnglish
A socio-ecological exploration to identify factors influencing the COVID-19 vaccine decision-making process among pregnant and lactating women: Findings from KenyaRupali J. Limaye, Alicia M. Paul, Rachel Gur-Arie, Eleonor Zavala, Clarice Lee, Berhaun Fesshaye, Prachi Singh, Wincate Njagi, Paul Odila, Paul Munyao, Rosemary Njogu, Stephen Mutwiwa, Lisa Noguchi, Christopher Morgan, Ruth A. Karron2022Journal articleEnglish
Characterizing Attitudes Toward Maternal RSV Vaccines Among Pregnant and Lactating Persons in Kenya: Key Considerations for Demand Generation Efforts for Vaccine AcceptanceRupali J. Limaye, Molly Sauer, Rosemary Njogu, Prachi Singh, Berhaun Fesshaye, Ruth A. Karron2023Journal articleEnglish
Conceptualizing the COVID-19 Pandemic: Perspectives of Pregnant and Lactating Women, Male Community Members, and Health Workers in KenyaAlicia M. Paul, Clarice Lee, Berhaun Fesshaye, Rachel Gur-Arie, Eleonor Zavala, Prachi Singh, Ruth A Karron, Rupali J. Limaye2022Journal articleEnglish
COVID-19 vaccine decision-making among pregnant and lactating women in BangladeshRupali J. Limaye, Prachi Singh, Alicia M. Paul, Berhaun Fesshaye, Clarice Lee, Eleonor Zavala, Sydney Wade, Hasmot Ali, Hafizur Rahman, Shirina Akter, Ruth A. Karron, Towfida Jahan Siddiqua2023Journal articleEnglish
COVID-19 vaccine eligibility of pregnant and lactating women in Bangladesh: Gap between policy and policy interpretation among policymakers and healthcare workersRupali J. Limaye, Berhaun Fesshaye, Prachi Singh, Eleonor Zavala, Shirina Akter, Towfida Jahan Siddiqua, Hafizur Rahman, Hasmot Ali, Ruth A. Karron2023Journal articleEnglish
Future GBS vaccines: Perspectives from pregnant and lactating people, healthcare providers, community members, and policymakers in KenyaBerhaun Fesshaye, Prachi Singh, Molly Sauer, Ruth A. Karron, Rupali J. Limaye2023Poster/infographicEnglish
Lack of clear national policy guidance on COVID-19 vaccines influences behaviors in pregnant and lactating women in KenyaEleonor Zavala, Berhaun Fesshaye, Clarice Lee, Stephen Mutwiwa, Wincate Njagi, Paul Munyao, Rosemary Njogu, Rachel Gur-Arie, Alicia M. Paul, Taylor A. Holroyd, Prachi Singh, Ruth A. Karron, Rupali J. Limaye2022Journal articleEnglish
Lessons learned from COVID-19 vaccine acceptance among pregnant and lactating women from two districts in Kenya to inform demand generation efforts for future maternal RSV vaccinesRupali J. Limaye, Prachi Singh, Berhaun Fesshaye, Ruth A. Karron2024Journal articleEnglish
Maternal Immunization Readiness Initiative (MIRI) Kenya Results DisseminationRupali J. Limaye, Berhaun Fesshaye, Prachi Singh, Emily Miller, Ruth A. Karron2023Poster/infographicEnglish
Maternal Immunization Readiness Initiative (MIRI) Kenya Results Dissemination Day 1 SlidesRupali J. Limaye, Prachi Singh, Berhaun Fesshaye, Eleonor Zavala, Clarice Lee, Ruth A. Karron2023PresentationEnglish
Maternal Immunization Readiness Initiative (MIRI) Kenya Results Dissemination Day 2 SlidesRupali J. Limaye, Prachi Singh, Berhaun Fesshaye, Eleonor Zavala, Clarice Lee, Ruth A. Karron2023PresentationEnglish
Maternal Immunization Readiness Initiative (MIRI) Kenya Results Dissemination Day 3 SlidesRupali J. Limaye, Prachi Singh, Berhaun Fesshaye, Eleonor Zavala, Clarice Lee, Ruth A. Karron2023PresentationEnglish
RSV awareness, risk perception, causes, and terms: Perspectives of pregnant and lactating women in Kenya to inform demand generation efforts for maternal RSV vaccinesRupali J. Limaye, Berhaun Fesshaye, Prachi Singh, Ruth A. Karron2023Journal articleEnglish
Sources of COVID-19 Vaccine Promotion for Pregnant and Lactating Women in BangladeshBerhaun Fesshaye, Sydney A. Wade, Clarice Lee, Prachi Singh, Eleonor Zavala, Hasmot Ali, Hafizur Rahman, Towfida Jahan Siddiqua, Shirina Akter, Ruth A. Karron, Rupali J. Limaye2023Journal articleEnglish

Added by: Berhaun Fesshaye

Added on: 2024-02-21 15:12:35

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