Dear Ghulam:

Please refer to the WHO website on the Effective Vaccine Management Initiative, where there a range of Standard Operating Procedures that may be helpful to you. I have attached to this mail the two that may specifically respond to your question: Using Vaccine Vial Monitors andMonitoring temperature exposure during vaccine transport

http://www.who.int/immunization/programmes_systems/supply_chain/evm/en/

WHO's recommendation would be check and note the status of VVM coloration both at issuance and receipt.

Kind regard,

Diana

WHO/EPI