Well-performing supply chains play a fundamental role in improving access to lifesaving products for all, and are a critical part of the COVID-19 response. However, supply chains can be a weak point in the system, and often are stretched beyond their ability to reach all people equitably. VillageReach has identified five promising design options that address common supply chain challenges, even for the hardest-to-reach communities. This document describes the five design options and considerations for their use.