Guidance

WHO guidance note: Vaccine diluents, revision 2015

A vaccine diluent is the liquid mixed with a lyophilized (freeze-dried) vaccine in order to reconstitute the lyophilized vaccine and provide the final vaccine for administration. A vaccine diluent may be sensitive to heat or freezing, and may require transportation and storage in the cold chain. This guidance note outlines the proper handling and use of vaccine diluent, including, but not limited to, critical steps for reconstituting vaccines safely.

Languages

  • English

Publication year

2015

Type

Guidance

By EVM criterion

EPI-CORE-SCL

The resource is included in the following table:

TitleAuthorYearTypeLanguage
Achieving immunization targets with the comprehensive effective vaccine management (EVM) frameworkUNICEF, World Health Organization (WHO)2016GuidanceEnglish, French
Cold room temperature mapping studiesWorld Health Organization (WHO)2018GuidanceEnglish
EVM Global Data AnalysisWorld Health Organization (WHO)2018GuidanceEnglish
EVM Model SOP manualWorld Health Organization (WHO)2013GuidanceEnglish, French
EVM1 assessment tools and user guidesWorld Health Organization (WHO)2019RepositoryEnglish
How to Develop a Continuous Improvement Plan (cIP)UNICEF, World Health Organization (WHO)2018GuidanceArabic, English, French
Immunization supply chain and logistics - A neglected but essential system for national immunization programmesWorld Health Organization (WHO)2014GuidanceEnglish, French
Off-label use of vaccinesPieter Neels, James Southern, Jon Abramson, Philippe Duclos, Joachim Hombach, Melanie Marti, Alanna Fitzgerald-Husek, Jacqueline Fournier-Caruana, Germaine Hanquet2017Journal articleEnglish
Perception of health workers on the use of 30-day temperature recordersWorld Health Organization (WHO)2018GuidanceEnglish
Perception of health workers on the use of remote temperature monitoring systemsWorld Health Organization (WHO)2018GuidanceEnglish
Solar direct-drive vaccine refrigerators and freezers2017GuidanceEnglish
System design approach to improve the immunization supply chainWorld Health Organization (WHO)2018GuidanceEnglish
Vaccine Management HandbookUNICEF, World Health Organization (WHO)2015GuidanceFrench
WHO guidance note: Vaccine diluents, revision 2015World Health Organization (WHO)2015GuidanceEnglish
WHO policy on the use of opened multi-dose vaccine vials (2014 Revision)World Health Organization (WHO)2014GuidanceFrench
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