Journal article
Effects of freezing on DPT and DPT-IPV vaccines, adsorbed
This paper summarizes evaluation of whether DPT and DPT-IPV from Connaught Laboratories Ltd. are visually altered by freezing in response to concern that some adsorbed DPT products can be visually unchanged, despite loss of potency from freeze damage. Data from 80 vials tested under various conditions suggest that the shake test is ineffective in field conditions. Authors recommend that a temperature-monitoring device be included with vaccines during transport, either a min-max thermometer, temperature logger, or Freeze WatchTM indicators.
Authors
Languages
- English
- French
Journal
Canada Communicable Disease Report
Volume
11
Type
Journal article
Categories
- Vaccines & delivery devices
Topic references
FREEZE-PREVENTION-POTENCY
Title | Author | Year | Type | Language |
---|---|---|---|---|
Assessing the potency and immunogenicity of inactivated poliovirus vaccine after exposure to freezing temperatures | Abhijeet Anand, Cynthia J. Snider, Dexiang Chen, Diana Kouiavskaia, Edmond F. Maes, Eric Stevens, Howard E. Gary Jr., Jacqueline Fournier-Caruana, Jessica A. White, Konstantin Chumakov, M. Steven Oberste, Marcus Estrada, William C. Weldon | Journal article | English | |
Cold chain study: danger of freezing vaccines | P. Milhomme | Journal article | English | |
Comparison of hepatitis B vaccine coverage and effectiveness among urban and rural Mongolian 2-year-olds | Ann Marie Kimball, Arslan Rinchin, J. Khulan, James S. Edstam, Nyamkhuu Dulmaa, Pagbajabyn Nymadawa | Journal article | English | |
Effects of freezing on DPT and DPT-IPV vaccines, adsorbed | A. Bell, D. Scheifele, R. Dimayuga | Journal article | English, French | |
Factors affecting the immunogenicity and potency of tetanus toxoid: implications for the elimination of neonatal and non-neonatal tetanus as public health problems | A. Galazka, F. van Loon, S. Cochi, V. Dietz | Journal article | English | |
Hepatitis B vaccine | Arlene A. McLean, Raymond Shaw Jr. | Journal article | English | |
Hepatitis B vaccine in healthy hospital employees | R. Normand, R. Silberman, S. A. Klotz | Journal article | English | |
Performance and potency of tetanus toxoid: implications for eliminating neonatal tetanus | F. van Loon, J. B. Milstien, J. Bennett, S. Cochi, V. Dietz | Journal article | English | |
Physical, chemical and immunological stability of CHO-derived hepatitis B surface antigen (HBsAg) particles | Dvorah Diminsky, Marian Gorecki, Neomi Moav, Yechezkel Barenholz | Journal article | English | |
Storage at -3 degrees C for 24 h alters the immunogenicity of pertussis vaccines | Christina Ann Boros, D. M. Roberton, M. Hanlon, Michael Steven Gold | Journal article | English |