Single dose schedule

Paul Bloem

Recent evidence has shown that a single-dose schedule can provide comparable efficacy to the two-dose regimen. A single-dose schedule could rapidly increase HPV vaccination rollout and access.

Resources on this page provide guidance and insights into the adoption of single-dose HPV vaccine schedules. The types of documents you may find in the table are:

  • Global Guidelines: WHO and other global recommendations.
  • Country-Specific Case Studies: Examples of countries implementing single-dose schedules.
  • Programmatic Implications: Detailed analysis of programmatic impacts (e.g., vaccine schedule optimization).

TitleAuthorYearTypeLanguage
Review of Existing Evidence on Single-Dose HPV VaccinationSingle dose consortium2022PresentationEnglish, French
HPV VACCINE SCHEDULE OPTIMIZATION Key considerations for decision-making, planning, and implementationPATH, JSI, UNICEF, Gavi, the Vaccine Alliance, Clinton Health Access Initiative (CHAI), Jhpiego, International Vaccine Access Center (IVAC), Centers for Disease Control and Prevention (CDC), John Hopkins Bloomberg School of Public Health2023GuidanceEnglish, French, Portuguese, Russian, Spanish
Considerations for Human Papillomavirus (HPV) Vaccine Product Choice: Second EditionWorld Health Organization (WHO)2024GuidanceEnglish
The Operational Impact of Switching from a Two-Dose to a One-Dose HPV Vaccination Schedule: Lessons Learned from Burkina Faso, Ethiopia, and Solomon Islands PATH2025ReportEnglish