Guidance

The immunity boost: the essential role of DTP-containing vaccine boosters

The primary series of three doses of DTP-containing vaccine (DTPcv) for infants is given in the first six months of life, most commonly as a combination Pentavalent or Hexavalent vaccine.
However, vaccine-induced immunity following the primary series wanes with time. To maintain protection, the World Health Organization (WHO) recommends three additional doses of vaccines against diphtheria and tetanus to boost protection and at least one booster against pertussis, following the primary DTPcv series.

This advocacy note summarizes the rationale behind these recommendations.  Additional resources to support country decision making for DTPcv booster dose introductions can be found at the links below.

Cliquez ici pour la note de plaidoyer et les ressources en français : https://www.technet-21.org/en/resources/guidance/le-renforcement-de-l-immunite-le-role-essentiel-des-doses-de-rappel-du-vaccin-antidiphterique-antitetanique-anticoquelucheux

WHO Position papers and supplementary materials

WHO Immunological Basis for Immunization Series

WHO Vaccine Preventable Disease Surveillance Standards (2018 revision)

Vaccine supply

Vaccine safety

Gavi programme funding

Burden of Disease databases

Implementation/programmatic resources

Publication year

2025

Type

Guidance

Categories

  • Programme management

Diseases

  • Diphtheria
  • Pertussis
  • Tetanus

Added by: Stephanie Shendale

Added on: 2025-03-21 12:34:08

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Links

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DTP booster advocacy note_no logos_June2025.pdf

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