Journal article

BCG protects against tuberculosis irrespective of HIV status: a matched case-control study in Mwanza

While BCG vaccine protects against severe tuberculosis (TB) in children, its effect against adult TB is questionable. Furthermore, it is not known if HIV co-infection modifies the effect of BCG. Among 352 pairs of Tanzanian TB cases and matched controls, the BCG scar was associated with a reduced risk of TB (OR 0.3, 95% CI 0.2 to 0.7, p=0.005), irrespective of HIV status (interaction, p=0.623). BCG vaccination considerably reduced the risk of TB, both among individuals with and without HIV infection.

Languages

  • English

Publication year

2013

Journal

Thorax.

Volume

3

Type

Journal article

Categories

  • Service delivery