Journal article
Cross-protective efficacy of two human papillomavirus vaccines: systematic review and meta-analysis
The study concludes that the bivalent vaccine seems more efficacious against non-vaccine HPV types 31, 33, and 45 than the quadrivalent vaccine, but the differences were not all significant and might be attributable to differences in trial design. Efficacy against persistent infections with types 31 and 45 seemed to decrease in bivalent trials with increased follow-up, suggesting a waning of cross-protection; more data are needed to establish duration of cross-protection.
Authors
Languages
- English
Publication year
2012
Journal
The Lancet Infectious Diseases
Volume
10
Type
Categories
Diseases
