HPV vaccine effect: is the glass half full or half empty?

In The Lancet , Julia Brotherton and colleagues report a decrease in precancerous cervical lesions in girls younger than 18 years after population-wide human papillomavirus (HPV) vaccination in Victoria, Australia, in 2007. The study suggests a 38% decrease in the rates of histologically confirmed high-grade cervical lesions in these girls during the 2 years after HPV vaccine introduction compared with the 3 years before vaccine introduction.