A CDC

program goal for 2010 is to achieve >95% participation in an

immunization information system (IIS) (defined as having two or

more recorded vaccinations) among children aged <6 years. IISs-

previously known as immunization registries- are confidential-

computerized information systems that collect and consolidate

vaccination data from multiple health-care providers- generate

reminder and recall notifications- and assess vaccination coverage

within a defined geographic area. Most IISs have additional

capabilities- such as vaccine management- adverse event reporting-

maintenance of birth-to-death vaccination histories- and

interoperability with other health information systems. IISs can

provide accurate data on which to make informed vaccination

decisions and better protect against vaccine-preventable diseases.

This report highlights selected data from CDC\'s 2006 Immunization

Information System Annual Report (IISAR)- a survey of grantees in

50 states- five cities- and the District of Columbia that receive

funding under the Public Health Service Act. The data indicated

that 65% of all U.S. children aged <6 years (approximately 15

million children) participated in an IIS in 2006- an increase from

56% in 2005. The majority of grantees (70%) reported that their

IISs have the capacity to track vaccinations for persons of all

ages. Data on vaccinations were entered within 30 days of vaccine

administration for 69% of children aged <6 years. However-

results for certain data completeness measures were low. These

findings underscore the need to continue to address challenges to

full IIS participation and ensure high-quality

information.