Journal article
Immunogenicity of a human rotavirus vaccine (RIX4414) after storage at 37°C for seven days
The lyophilized formulation of the human rotavirus vaccine, RIX4414 (Rotarix™), is recommended to be stored at 2°C-8°C for optimal immunogenicity. In some settings with inadequate infrastructure for vaccine storage, unforeseen circumstances may cause cold chain breakage, resulting in the vaccine to be left at ambient temperatures. This study evaluated the heat stability of lyophilized RIX4414 vaccine in terms of immunogenicity when stored at tropical room temperature (37°C) for 7 days before reconstitution.
Authors
Languages
- English
Publication year
2011
Journal
Hum Vaccin.
Volume
7
Issue
1
Type
Journal article
Categories
- Supply chain & logistics
Diseases
- Rotavirus
Tags
- Cold room / freezer room
- Delivery device
- New vaccine introduction
