Journal article

Universal hepatitis B vaccination: The only way to eliminate hepatocellular carcinoma?

Chronic hepatitis B infection affects over 240 million people worldwide, with long-term morbidity such as cirrhosis and hepatocellular carcinoma (HCC) accounting for around 600,000 deaths annually [1]. Since the discovery of hepatitis B virus (HBV) by Blumberg in 1965, progress has been impressive with the availability in the 1980 of HBV vaccine and in the 2000 the development of potent antiviral agents resulting in an improved long-term outcome. Despite the fact that the WHO recommends universal vaccination against hepatitis B to ultimately eliminate HBV (this recommendation has been progressively implemented to reach 168 countries), the global burden of HBV-related disease is still substantial.

Languages

  • English

Journal

Journal of Hepatology

Volume

6

Type

Journal article

Categories

  • Service delivery

Diseases

  • Hepatitis B

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