The Communication and Coordination Action Plan (CCAP) in supporting regional vaccine security and self-reliance aims to provide the conceptual framework to communicate messages or information about overall activities, public relations, campaigns, best practices, lesson learned and vision of the CCAP to key audiences, including governments, public and private sectors, academic institutions, international organizations, pharmaceutical companies, the existing networks, Non- Governmental Organizations (NGOs), global audiences, stakeholders, media and general citizens. The CCAP will serve as neutral media in sharing information and perspectives among the relevant partnerships involving a life cycle of vaccine. With hope that the establishment of an effective communication and coordination platform using appropriate communicable channels, models and messages e.g., the important of vaccine security and self-reliance, value of vaccination, vaccine registration processes and procurement will help improve outcomes of